N6-Cbz-L-Lysine

Names

[ Name ]:
N6-Cbz-L-Lysine

[Synonym ]:
N(ε)-Benzyloxycarbonyl-L-lysine
L-lysine, N-[hydroxy(phenylmethoxy)methylene]-, (E)-
6-N-Cbz-L-lysine
N6-[(phenylmethoxy)carbonyl]-L-lysine
L-Lysine, N-[(phenylmethoxy)carbonyl]-
N-[(Benzyloxy)carbonyl]-L-lysine
N6-(Benzyloxycarbonyl)-L-lysine
MFCD00002638
N6-Carbobenzyloxy-L-lysine
Nepsilon-Carbobenzyloxy-L-lysine
LYSINE(Z)-OH
N6-Cbz-L-Lysine
EINECS 214-585-7
LYS(Z)
Nε-Carbobenzoxy-L-lysine
Nε-Cbz-L-lysine
L-LYSINE(CBZ)
H-LYS(Z)-OH
H-LYS(CBZ)-OH
H-L-Lys(Z)-OH
(S)-N6-Benzyloxycarbonyllysine
L-Lys(Cbz)-OH
L-LYS(Z)

Biological Activity

[Description]:

H-Lys(Z)-OH is a lysine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
499.6±45.0 °C at 760 mmHg

[ Melting Point ]:
259ºC (dec.)

[ Molecular Formula ]:
C₁₄H₂₀N₂O₄

[ Molecular Weight ]:
280.320

[ Flash Point ]:
255.9±28.7 °C

[ Exact Mass ]:
280.142303

[ PSA ]:
101.65000

[ LogP ]:
1.36

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.550

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Transfection of cells mediated by biodegradable polymer materials with surface-bound polyethyleneimine.

Biotechnol. Prog. 16 , 254-257, (2000)

Poly(epsilon-CBZ-L-lysine) can be mixed with biodegradable polymers such as poly(D,L-lactic-co-glycolic acid) or poly(L-lactic acid) and formed into films, foams, or microspheres. Surface amino groups...

Production of microspheres with surface amino groups from blends of Poly(Lactide-co-glycolide) and Poly(epsilon-CBZ-L-lysine) and use for encapsulation.

Biotechnol. Prog. 15 , 763-767, (1999)

Microspheres were formed from blends of the biodegradable polymer poly(DL-lactic-co-glycolic acid) (PLGA) together with poly(epsilon-CBZ-L-lysine) (PCBZL) by a double-emulsification/solvent evaporatio...

Transformation of N epsilon-CBZ-L-lysine to CBZ-L-oxylysine using L-amino acid oxidase from Providencia alcalifaciens and L-2-hydroxy-isocaproate dehydrogenase from Lactobacillus confusus.

Appl. Microbiol. Biotechnol. 37(5) , 599-603, (1992)

Biotransformations were developed to oxidize N epsilon-carbobenzoxy(CBZ)-L-lysine and to reduce the product keto acid to L-CBZ-oxylysine. Lysyl oxidase (L-lysine: O2 oxidoreductase, EC 1.4.3.14) from ...