N6-Cbz-L-Lysine benzyl ester hydrochloride

Names

[ Name ]:
N6-Cbz-L-Lysine benzyl ester hydrochloride

[Synonym ]:
L-Lysine, N-[(phenylmethoxy)carbonyl]-, phenylmethyl ester, hydrochloride (1:1)
MFCD00038981
EINECS 228-859-9
Benzyl N-[(benzyloxy)carbonyl]-L-lysinate hydrochloride (1:1)
N6-Carbobenzyloxy-L-lysine Benzyl Ester Hydrochloride
H-Lys(Z)-OBzl·HCl

Biological Activity

[Description]:

N6-Carbobenzoxy-L-lysine benzyl ester hydrochloride is a lysine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.163g/cm3

[ Boiling Point ]:
511.7ºC at 760 mmHg

[ Melting Point ]:
138-140ºC

[ Molecular Formula ]:
C₂₁H₂₇ClN₂O₄

[ Molecular Weight ]:
406.903

[ Flash Point ]:
263.2ºC

[ Exact Mass ]:
406.165924

[ PSA ]:
90.65000

[ LogP ]:
5.04700

[ Index of Refraction ]:
1.562

[ Storage condition ]:
Store at RT.

MSDS

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Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OL5685000

CHEMICAL NAME :: Lysine, N(sup 6)-(phenylacetoxy)-, benzyl ester, monohydrochloride, L-

CAS REGISTRY NUMBER :: 6366-70-7

LAST UPDATED :: 198910

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H26-N2-O4.Cl-H

MOLECULAR WEIGHT :: 406.95

WISWESSER LINE NOTATION :: R1VOM4YZVO1R &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01629

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
OL5685000

[ HS Code ]:
2924299090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%