N6-Cbz-L-Lysine

N6-Cbz-L-Lysine Structure
N6-Cbz-L-Lysine structure
Common Name N6-Cbz-L-Lysine
CAS Number 1155-64-2 Molecular Weight 280.320
Density 1.2±0.1 g/cm3 Boiling Point 499.6±45.0 °C at 760 mmHg
Molecular Formula C14H20N2O4 Melting Point 259ºC (dec.)
MSDS Chinese USA Flash Point 255.9±28.7 °C

Transfection of cells mediated by biodegradable polymer materials with surface-bound polyethyleneimine.

Biotechnol. Prog. 16 , 254-257, (2000)

Poly(epsilon-CBZ-L-lysine) can be mixed with biodegradable polymers such as poly(D,L-lactic-co-glycolic acid) or poly(L-lactic acid) and formed into films, foams, or microspheres. Surface amino groups may then be deprotected with acid or lithium/liquid ammoni...

Production of microspheres with surface amino groups from blends of Poly(Lactide-co-glycolide) and Poly(epsilon-CBZ-L-lysine) and use for encapsulation.

Biotechnol. Prog. 15 , 763-767, (1999)

Microspheres were formed from blends of the biodegradable polymer poly(DL-lactic-co-glycolic acid) (PLGA) together with poly(epsilon-CBZ-L-lysine) (PCBZL) by a double-emulsification/solvent evaporation technique. The size of the microspheres formed by this me...

Transformation of N epsilon-CBZ-L-lysine to CBZ-L-oxylysine using L-amino acid oxidase from Providencia alcalifaciens and L-2-hydroxy-isocaproate dehydrogenase from Lactobacillus confusus.

Appl. Microbiol. Biotechnol. 37(5) , 599-603, (1992)

Biotransformations were developed to oxidize N epsilon-carbobenzoxy(CBZ)-L-lysine and to reduce the product keto acid to L-CBZ-oxylysine. Lysyl oxidase (L-lysine: O2 oxidoreductase, EC 1.4.3.14) from Trichoderma viride was relatively specific for L-lysine and...