L-Gulonic g-lactone

Names

[ Name ]:
L-Gulonic g-lactone

[Synonym ]:
L-(+)-Gulonic Acid gaMMa-Lactone
L-Gulonic g-lactone
L-(+)-Gulonic Acid γ-Lactone
MFCD00064331
L-Gulonic acid γ-lactone
(3S,4R,5R)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one
(3S,4R,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-one
L-Gulonolactone
(3S,4R,5R)-5-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxydihydrofuran-2(3H)-on (non-preferred name)
(3S,4R,5R)-5-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxydihydrofuran-2(3H)-one (non-preferred name)
L-gulono-1,4-lactone
(3S,4R,5R)-5-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxydihydro-2(3H)-furanone
L(+)-Gulonic acid gamma-lactone

Biological Activity

[Description]:

L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vatamin) C. In other words, L-Gulono-1,4-lactone is a direct precursor of vitamin C in animals, in plants and in some protists.

[Related Catalog]:

Research Areas >> Metabolic Disease

Natural Products >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Wolucka BA, et al. Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase. FEBS J. 2006 Oct;273(19):4435-45. Epub 2006 Sep 5.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
467.9±18.0 °C at 760 mmHg

[ Melting Point ]:
187-190ºC(lit.)

[ Molecular Formula ]:
C₆H₁₀O₆

[ Molecular Weight ]:
178.140

[ Flash Point ]:
201.5±14.7 °C

[ Exact Mass ]:
178.047745

[ PSA ]:
107.22000

[ LogP ]:
-3.15

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.625

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
22-24/25

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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