Danofloxacine
Names
[ CAS No. ]:
112398-08-0
[ Name ]:
Danofloxacine
[Synonym ]:
1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
danofloxacin
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-
1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
(1S)-1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl)-4-oxo-3-quinolinecarboxylic acid
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
569.3±50.0 °C at 760 mmHg
[ Melting Point ]:
268-272ºC
[ Molecular Formula ]:
C19H20FN3O3
[ Molecular Weight ]:
357.379
[ Flash Point ]:
298.1±30.1 °C
[ Exact Mass ]:
357.148865
[ PSA ]:
65.78000
[ LogP ]:
1.20
[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C
[ Index of Refraction ]:
1.679
[ Water Solubility ]:
Soluble in water, acetic acid and DMSO
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn,Xi
[ Risk Phrases ]:
20/21/22-36/37/38
[ Safety Phrases ]:
22-24/25
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Chromatogr. A. 1379 , 83-91, (2015)
This work involved the optimization and validation of two methods according to the Commission Decision 2002/657/EC directives for determining fluoroquinolones residues in samples of poultry muscle and...
Simultaneous determination of 38 veterinary antibiotic residues in raw milk by UPLC-MS/MS.Food Chem. 181 , 119-26, (2015)
A selective and rapid method has been developed to determine, simultaneously, 38 veterinary antibiotic residues in raw milk by ultra-high-performance liquid chromatography-tandem mass spectrometry (UP...
Decay mechanisms of protonated 4-quinolone antibiotics after electrospray ionization and ion activation.J. Am. Soc. Mass Spectrom. 25(11) , 1974-86, (2014)
This study presents a detailed experimental investigation of charge isomers of protonated 4-quinolone antibiotics molecules formed during electrospray ionization (ESI) with proposed dissociation mecha...