2-Amino-5-chloropyridine

Names

[ Name ]:
2-Amino-5-chloropyridine

[Synonym ]:
2-Amino-5-chloropyridine
5-chloropyridin-2-amine
6-chloropyridin-2-ylamine
2-Pyridinamine, 5-chloro-
5-Chloro-2-pyridinamine
5-CHLORO-A-PYRIDYLAMINE
EINECS 214-020-4
2-AMINO-5-CHLIROPYRIDINE
2-Amino-5-Chloro Pyriine
2-amino-5-chloro-pyridine
5-chloropyridin-2-ylamine
5-CHLORO-2-AMINOPYRIDINE
MFCD00006324
5-CHLORO-2-PYRIDYLAMINE
Edoxaban Impurity 18

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
257.8±0.0 °C at 760 mmHg

[ Melting Point ]:
135-138 °C(lit.)

[ Molecular Formula ]:
C₅H₅ClN₂

[ Molecular Weight ]:
128.560

[ Flash Point ]:
94.7±21.8 °C

[ Exact Mass ]:
128.014130

[ PSA ]:
38.91000

[ LogP ]:
1.68

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.607

[ Water Solubility ]:
1 g/L (20 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S22-S24/25-S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Simultaneous determination of zopiclone and its degradation product and main impurity (2-amino-5-chloropyridine) by micellar liquid chromatography with time-programmed fluorescence detection: preliminary investigation for biological monitoring.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 907 , 49-55, (2012)

A simple and reliable HPLC method was developed and validated for the simultaneous determination of the hypnotic drug, zopiclone (ZPC) and its degradation product and main impurity, 2-amino-5-chloropy...

Capillary electrophoretic enantioselective determination of zopiclone and its impurities.

Electrophoresis 33(11) , 1606-12, (2012)

A capillary electrophoretic enantioselective method with UV detection was developed and validated for the simultaneous quantification of zopiclone enantiomers and its impurities, zopiclone-N-oxide ena...

Degradation of zopiclone during storage of spiked and authentic whole blood and matching dried blood spots.

Int. J. Legal Med. 127(1) , 69-76, (2013)

Z-drugs such as zopiclone are increasingly involved in forensic cases. Its degradation occurs in solvents and biological fluids. It is assumed that hydrolysis largely accounts for the breakdown of zop...