2-Nitro-3-pyridinol

Names

[ Name ]:
2-Nitro-3-pyridinol

[Synonym ]:
3-Hydroxy-2-Nitropyrine
2-Nitro-3-pyridinol
2-nitro-3-pyridino
3-hydroxyl-2-nitropyridine
3-Hydroxy-2-nitropyridine
2-nitropyridin-3-ol
EINECS 239-191-2
2-hydroxy-2-nitropyridine
3-Hydroxy-2-nitropyr
3-PYRIDINOL,2-NITRO
2-NITRO-3-HYDROPYRIDINE
3-Pyridinol, 2-nitro-
2-Nitro-pyridin-3-ol
MFCD00006258
3-hydroxy 2-nitropyridine

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
383.2±22.0 °C at 760 mmHg

[ Melting Point ]:
69-71 °C(lit.)

[ Molecular Formula ]:
C₅H₄N₂O₃

[ Molecular Weight ]:
140.097

[ Flash Point ]:
185.6±22.3 °C

[ Exact Mass ]:
140.022186

[ PSA ]:
78.94000

[ LogP ]:
0.93

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.623

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU7715000

CHEMICAL NAME :: 3-Pyridinol, 2-nitro-

CAS REGISTRY NUMBER :: 15128-82-2

BEILSTEIN REFERENCE NO. :: 0124473

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H4-N2-O3

MOLECULAR WEIGHT :: 140.11

WISWESSER LINE NOTATION :: T6NJ BNW CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04089

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
UU7715000

[ WGK Germany ]:
3

[ RTECS ]:
UU7715000

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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The synthesis and biological evaluation of novel sulfonate analogues of E-7010 are reported. Several of the compounds are potent inhibitors of cell proliferation and tubulin polymerization. Importantl...