TFAP

TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.

Signaling Pathways >> Immunology/Inflammation >> COX

Natural Products >> Others

Research Areas >> Metabolic Disease

COX-1:0.8 μM (IC50)

Human Endogenous Metabolite

TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM, while that against COX-2 is over 200 μM.

[1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.

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