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Related CAS#:

1011244-68-0

1011244-68-0 structure
1011244-68-0 structure
  • Name: TFAP
  • Chemical Name: N-(5-amino-2-pyridinyl)-4-trifluoromethylbenzamide
  • CAS Number: 1011244-68-0
  • Molecular Formula: C13H10F3N3O
  • Molecular Weight: 281.23300
  • Catalog: Signaling Pathways Immunology/Inflammation COX
  • Create Date: 2018-05-15 06:02:28
  • Modify Date: 2024-01-05 15:47:34
  • TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.

Name N-(5-amino-2-pyridinyl)-4-trifluoromethylbenzamide
Synonyms tfap
tfap
Description TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.
Related Catalog
Target

COX-1:0.8 μM (IC50)

Human Endogenous Metabolite

In Vitro TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM, while that against COX-2 is over 200 μM.
References

[1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.

Molecular Formula C13H10F3N3O
Molecular Weight 281.23300
Exact Mass 281.07800
PSA 68.01000
LogP 3.58910
Storage condition 2-8℃