TFAP

Modify Date: 2024-01-05 15:47:34

TFAP Structure
TFAP structure
Common Name TFAP
CAS Number 1011244-68-0 Molecular Weight 281.23300
Density N/A Boiling Point N/A
Molecular Formula C13H10F3N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TFAP


TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.

 Names

Name N-(5-amino-2-pyridinyl)-4-trifluoromethylbenzamide
Synonym More Synonyms

 TFAP Biological Activity

Description TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.
Related Catalog
Target

COX-1:0.8 μM (IC50)

Human Endogenous Metabolite

In Vitro TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM, while that against COX-2 is over 200 μM.
References

[1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.

 Chemical & Physical Properties

Molecular Formula C13H10F3N3O
Molecular Weight 281.23300
Exact Mass 281.07800
PSA 68.01000
LogP 3.58910
Storage condition 2-8℃

 Safety Information

 Synonyms

tfap
tfap
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Price: ¥990/10 mM * 1 mL in DMSO

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