MRGPRX1 agonist 2

Modify Date: 2025-08-27 11:40:40

MRGPRX1 agonist 2 Structure
MRGPRX1 agonist 2 structure
Common Name MRGPRX1 agonist 2
CAS Number 302952-43-8 Molecular Weight 270.35
Density N/A Boiling Point N/A
Molecular Formula C15H14N2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MRGPRX1 agonist 2


MRGPRX1 agonist 2 (compound 1a) is a potent Mas-related G protein-coupled receptor X1 (MRGPRX1) positive allosteric modulator with an EC50 value of 0.48 μM. MRGPRX1 agonist 2 can be used for researching neuropathic pain[1].

 Names

Name MRGPRX1 agonist 2

 MRGPRX1 agonist 2 Biological Activity

Description MRGPRX1 agonist 2 (compound 1a) is a potent Mas-related G protein-coupled receptor X1 (MRGPRX1) positive allosteric modulator with an EC50 value of 0.48 μM. MRGPRX1 agonist 2 can be used for researching neuropathic pain[1].
Related Catalog
Target

EC50: 0.48 μM (MRGPRX1)[1]

References

[1]. Berhane I, et al. Thieno[2,3-d]pyrimidine-Based Positive Allosteric Modulators of Human Mas-Related G Protein-Coupled Receptor X1 (MRGPRX1). J Med Chem. 2022;65(4):3218-3228.

 Chemical & Physical Properties

Molecular Formula C15H14N2OS
Molecular Weight 270.35
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