TrxR-IN-3
Modify Date: 2025-08-26 18:12:13
TrxR-IN-3 structure
|
Common Name | TrxR-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2445565-58-0 | Molecular Weight | 268.23 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H11F3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TrxR-IN-3TrxR-IN-3 (Compound 2c) is a potent inhibitor of TrxR. TrxR-IN-3 exhibits potent antiproliferative activities against five human cancer cell lines, especially against breast tumor cells. TrxR-IN-3 increases ROS levels and resulted in marked apoptosis by regulating apoptosis-related proteins expressed in the breast cancer cells. TrxR-IN-3 also triggers the formation of autophagosomes and autolysosomes by promoting the expression of LC3-II and Beclin-1 and diminishing the expression of LC3-I and p62 proteins[1]. |
| Name | TrxR-IN-3 |
|---|
| Description | TrxR-IN-3 (Compound 2c) is a potent inhibitor of TrxR. TrxR-IN-3 exhibits potent antiproliferative activities against five human cancer cell lines, especially against breast tumor cells. TrxR-IN-3 increases ROS levels and resulted in marked apoptosis by regulating apoptosis-related proteins expressed in the breast cancer cells. TrxR-IN-3 also triggers the formation of autophagosomes and autolysosomes by promoting the expression of LC3-II and Beclin-1 and diminishing the expression of LC3-I and p62 proteins[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C14H11F3O2 |
|---|---|
| Molecular Weight | 268.23 |