EGFR/HER2/TS-IN-2 structure
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Common Name | EGFR/HER2/TS-IN-2 | ||
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CAS Number | 2444364-04-7 | Molecular Weight | 511.62 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C26H21N7OS2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of EGFR/HER2/TS-IN-2EGFR/HER2/TS-IN-2 (compound 17) is a potent EGFR/HER2 and TS (Thymidylate synthase) inhibitor, with IC50 values of 0.173, 0.125, and 1.12 μM, respectively. EGFR/HER2/TS-IN-2 shows cytotoxic activity against MDA-MB-231 cancer cell lines, with an IC50 of 1.69 µM[1]. |
Name | EGFR/HER2/TS-IN-2 |
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Description | EGFR/HER2/TS-IN-2 (compound 17) is a potent EGFR/HER2 and TS (Thymidylate synthase) inhibitor, with IC50 values of 0.173, 0.125, and 1.12 μM, respectively. EGFR/HER2/TS-IN-2 shows cytotoxic activity against MDA-MB-231 cancer cell lines, with an IC50 of 1.69 µM[1]. |
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Related Catalog | |
Target |
EGFR:0.173 ± 0. μM (IC50) HER2:0.125 ± 0. μM (IC50) |
In Vitro | EGFR/HER2/TS-IN-2 (compound 17) shows the GI (growth inhibition)=53.20 and 49.35% towards ovarian cancer IGROV1 and renal cancer UO-31, respectively[1]. |
References |
Molecular Formula | C26H21N7OS2 |
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Molecular Weight | 511.62 |