TGFβ-IN-2
Modify Date: 2025-08-19 17:00:47
TGFβ-IN-2 structure
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Common Name | TGFβ-IN-2 | ||
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| CAS Number | 2387678-02-4 | Molecular Weight | 378.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H22N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TGFβ-IN-2TGFβ-IN-2 (Compound 9d) inhibits TGF-β-induced total collagen accumulation in NRK-49F cells with the IC50 of 4.31 μM. TGFβ-IN-2 suppresses the TGF-β-induced protein expression of COL1A1, α-SMA, and p-Smad3 in vitro. TGFβ-IN-2 can be used as a potential effective compound for anti-fibrosis in vivo by oral administration[1]. |
| Name | TGFβ-IN-2 |
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| Description | TGFβ-IN-2 (Compound 9d) inhibits TGF-β-induced total collagen accumulation in NRK-49F cells with the IC50 of 4.31 μM. TGFβ-IN-2 suppresses the TGF-β-induced protein expression of COL1A1, α-SMA, and p-Smad3 in vitro. TGFβ-IN-2 can be used as a potential effective compound for anti-fibrosis in vivo by oral administration[1]. |
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| Molecular Formula | C22H22N2O4 |
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| Molecular Weight | 378.42 |