ATG7-IN-2

Modify Date: 2024-01-28 13:12:30

Use of ATG7-IN-2

ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].

Name	ATG7-IN-2

Description	ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy
Target	IC50: 0.089 ± 0.036 μM (ATG7), 0.335 ± 0.049 μM (Thioester), 2.6 μM (LC3B)[1]
References	[1]. Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.

Molecular Formula	C₁₁H₁₆N₆O₇S
Molecular Weight	376.35