ATG7-IN-2

Names

[ Name ]:
ATG7-IN-2

Biological Activity

[Description]:

ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Autophagy >> Autophagy

[Target]

IC50: 0.089 ± 0.036 μM (ATG7), 0.335 ± 0.049 μM (Thioester), 2.6 μM (LC3B)[1]

[References]

[1]. Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₆N₆O₇S

[ Molecular Weight ]:
376.35

Related Compounds

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