2226227-75-2

2226227-75-2 structure
2226227-75-2 structure
  • Name: ATG7-IN-2
  • Chemical Name: ATG7-IN-2
  • CAS Number: 2226227-75-2
  • Molecular Formula: C11H16N6O7S
  • Molecular Weight: 376.35
  • Catalog: Signaling Pathways Autophagy Autophagy
  • Create Date: 2022-07-10 23:09:17
  • Modify Date: 2025-08-26 20:17:34
  • ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].

Name ATG7-IN-2
Description ATG7-IN-2 (compound 1) is a potent ATG7 inhibitor, with an IC50 of 0.089 μM. ATG7-IN-2 inhibits autophagy marker LC3B[1].
Related Catalog
Target

IC50: 0.089 ± 0.036 μM (ATG7), 0.335 ± 0.049 μM (Thioester), 2.6 μM (LC3B)[1]

References

[1]. Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.

Molecular Formula C11H16N6O7S
Molecular Weight 376.35
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