GNE 0723 structure
|
Common Name | GNE 0723 | ||
---|---|---|---|---|
CAS Number | 1883518-31-7 | Molecular Weight | 467.776 | |
Density | 1.8±0.1 g/cm3 | Boiling Point | 505.2±60.0 °C at 760 mmHg | |
Molecular Formula | C16H8ClF6N5OS | Melting Point | N/A | |
MSDS | N/A | Flash Point | 259.4±32.9 °C |
Use of GNE 0723GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively. |
Name | GNE 0723 |
---|---|
Synonym | More Synonyms |
Description | GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively. |
---|---|
Related Catalog | |
Target |
EC50: 21 nM (GluN2A), 7.4 μM (GluN2C), 6.2 μM (GluN2D)[1] |
In Vitro | GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively[1]. |
References |
Density | 1.8±0.1 g/cm3 |
---|---|
Boiling Point | 505.2±60.0 °C at 760 mmHg |
Molecular Formula | C16H8ClF6N5OS |
Molecular Weight | 467.776 |
Flash Point | 259.4±32.9 °C |
Exact Mass | 467.004242 |
LogP | 2.89 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Index of Refraction | 1.680 |
Cyclopropanecarbonitrile, 2-[7-[[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl]-5-oxo-2-(trifluoromethyl)-5H-thiazolo[3,2-a]pyrimidin-3-yl]-, (1R,2R)- |
(1R,2R)-2-[7-{[5-Chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-5-oxo-2-(trifluoromethyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-3-yl]cyclopropanecarbonitrile |
MFCD30829912 |