hBChE-IN-1
Modify Date: 2024-09-19 00:19:57
hBChE-IN-1 structure
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Common Name | hBChE-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 1776948-12-9 | Molecular Weight | 466.70 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H34N2OS2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of hBChE-IN-1hBChE-IN-1 (compound 4), a quinolizidinyl derivative, is a potent hBChE inhibitor (IC50=7 nM) and highly selective over hAChE. hBChE-IN-1 shows inhibitory activity against tau and Aβ40 protein aggregation, with IC50 values of 20 and 4.3 μM, respectively. hBChE-IN-1 can be used for Alzheimer's disease research[1]. |
| Name | hBChE-IN-1 |
|---|
| Description | hBChE-IN-1 (compound 4), a quinolizidinyl derivative, is a potent hBChE inhibitor (IC50=7 nM) and highly selective over hAChE. hBChE-IN-1 shows inhibitory activity against tau and Aβ40 protein aggregation, with IC50 values of 20 and 4.3 μM, respectively. hBChE-IN-1 can be used for Alzheimer's disease research[1]. |
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| Related Catalog | |
| Target |
hBCHE:0.0070 ± 0 μM (IC50) equine serum BChE:0.088 μM (IC50) EeAChE:0.18 μM (IC50) hAChE:7.84 ± 0.8 μM (IC50) |
| References |
| Molecular Formula | C27H34N2OS2 |
|---|---|
| Molecular Weight | 466.70 |