1776948-12-9
1776948-12-9 structure
- Name: hBChE-IN-1
- Chemical Name: hBChE-IN-1
- CAS Number: 1776948-12-9
- Molecular Formula: C27H34N2OS2
- Molecular Weight: 466.70
- Catalog: Signaling Pathways Neuronal Signaling AChE
- Create Date: 2023-07-11 21:46:55
- Modify Date: 2024-09-19 00:19:57
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hBChE-IN-1 (compound 4), a quinolizidinyl derivative, is a potent hBChE inhibitor (IC50=7 nM) and highly selective over hAChE. hBChE-IN-1 shows inhibitory activity against tau and Aβ40 protein aggregation, with IC50 values of 20 and 4.3 μM, respectively. hBChE-IN-1 can be used for Alzheimer's disease research[1].
| Name | hBChE-IN-1 |
|---|
| Description | hBChE-IN-1 (compound 4), a quinolizidinyl derivative, is a potent hBChE inhibitor (IC50=7 nM) and highly selective over hAChE. hBChE-IN-1 shows inhibitory activity against tau and Aβ40 protein aggregation, with IC50 values of 20 and 4.3 μM, respectively. hBChE-IN-1 can be used for Alzheimer's disease research[1]. |
|---|---|
| Related Catalog | |
| Target |
hBCHE:0.0070 ± 0 μM (IC50) equine serum BChE:0.088 μM (IC50) EeAChE:0.18 μM (IC50) hAChE:7.84 ± 0.8 μM (IC50) |
| References |
| Molecular Formula | C27H34N2OS2 |
|---|---|
| Molecular Weight | 466.70 |