Trimethoprim-13C3

Modify Date: 2024-01-21 08:00:41

Trimethoprim-13C3 Structure
Trimethoprim-13C3 structure
Common Name Trimethoprim-13C3
CAS Number 1189970-95-3 Molecular Weight 293.30
Density N/A Boiling Point N/A
Molecular Formula C1113C3H18N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Trimethoprim-13C3


Trimethoprim-13C3is the deuterium labeledTrimethoprim(HY-B0510)[1]. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc[2][3][4][5].

 Names

Name Trimethoprim-13C3
Synonym More Synonyms

 Trimethoprim-13C3 Biological Activity

Description Trimethoprim-13C3is the deuterium labeledTrimethoprim(HY-B0510)[1]. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc[2][3][4][5].
Related Catalog
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Molecular Formula C1113C3H18N4O3
Molecular Weight 293.30
Exact Mass 293.14800
PSA 106.97000
LogP 1.11780

 Synonyms

5-[[3,4,5-tri(methoxy)phenyl]methyl]pyrimidine-2,4-diamine