27653-68-5

27653-68-5 structure

Name: Trimethoprim N-oxide
Chemical Name: Trimethoprim N-oxide
CAS Number: 27653-68-5
Molecular Formula: C₁₄H₁₈N₄O₄
Molecular Weight: 306.31700
Catalog: Research Areas Infection
Create Date: 2018-04-21 08:00:00
Modify Date: 2025-08-20 12:58:45
Trimethoprim N-oxide (Trimethoprim 1-N-oxide) belongs to human urinary metabolites. Trimethoprim N-oxide is generated by oxidation of nitrogen atoms in the pyrimidine ring. Trimethoprim N-oxide is formed predominantly by CYP1A2 in human liver microsomes[1].

Name	Trimethoprim N-oxide
Synonyms	2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine 1-oxide 2,4-Pyrimidinediamine, 5-[(3,4,5-trimethoxyphenyl)methyl]-, 1-oxide

Description	Trimethoprim N-oxide (Trimethoprim 1-N-oxide) belongs to human urinary metabolites. Trimethoprim N-oxide is generated by oxidation of nitrogen atoms in the pyrimidine ring. Trimethoprim N-oxide is formed predominantly by CYP1A2 in human liver microsomes[1].
Related Catalog	Research Areas >> Infection
References	[1]. Goldman JL, et al. In Vitro Hepatic Oxidative Biotransformation of Trimethoprim. Drug Metab Dispos. 2015 Sep;43(9):1372-80.