1-Deoxynojirimycin
1-Deoxynojirimycin structure
|
Common Name | 1-Deoxynojirimycin | ||
|---|---|---|---|---|
| CAS Number | 19130-96-2 | Molecular Weight | 163.172 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 361.1±42.0 °C at 760 mmHg | |
| Molecular Formula | C6H13NO4 | Melting Point | 195-196°C | |
| MSDS | N/A | Flash Point | 197.3±18.5 °C | |
Use of 1-Deoxynojirimycin1-Deoxynojirimycin (DNJ, Duvoglustat) is a potent α-glucosidase inhibitor, suppresses postprandial blood glucose, thereby possibly preventing diabetes mellitus. Target: α-glucosidase1-Deoxynojirimycin is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ, and on alternate routes of production, such as via Bacillusspecies. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | duvoglustat |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 1-Deoxynojirimycin (DNJ, Duvoglustat) is a potent α-glucosidase inhibitor, suppresses postprandial blood glucose, thereby possibly preventing diabetes mellitus. Target: α-glucosidase1-Deoxynojirimycin is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ, and on alternate routes of production, such as via Bacillusspecies. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 361.1±42.0 °C at 760 mmHg |
| Melting Point | 195-196°C |
| Molecular Formula | C6H13NO4 |
| Molecular Weight | 163.172 |
| Flash Point | 197.3±18.5 °C |
| Exact Mass | 163.084457 |
| PSA | 92.95000 |
| LogP | -2.10 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.582 |
| InChIKey | LXBIFEVIBLOUGU-UHFFFAOYSA-N |
| SMILES | OCC1NCC(O)C(O)C1O |
| Storage condition | Desiccate at +4°C |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S26-S37/39-S24/25 |
| WGK Germany | 3 |
| HS Code | 2933399090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 6 | |
|---|---|
| DownStream 10 | |
CAS#:132198-14-2
CAS#:75016-28-3
CAS#:69567-11-9
CAS#:15218-38-9
CAS#:81703-56-2
CAS#:72458-46-9
CAS#:80312-32-9
CAS#:72432-03-2
CAS#:72599-27-0
CAS#:69567-10-8
CAS#:130539-12-7
CAS#:128985-16-0
CAS#:73285-50-4
CAS#:105265-96-1![(2R,4aR,7S,8R,8aR)-Hexahydro-7,8-dihydroxy-2-phenyl-5H-1,3-dioxino[5,4-b]pyridine-5-carboxylic Acid Phenylmethyl Ester structure](https://image.chemsrc.com/caspic/191/138381-83-6.png)
CAS#:138381-83-6
CAS#:122371-65-7This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (2R,3R,4R,5S)-2-Hydroxymethyl-3,4,5-trihydroxypiperidine |
| D-5-Amino-1,5-dideoxyglucopyranose |
| deoxynojirimycin |
| MFCD00063474 |
| MORANOLINE |
| (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol |
| Duvoglustat |
| (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol |
| 1,5-Dideoxy-1,5-imino-D-glucitol |
| (+)-1-deoxynojirimycin |
| 1-Deoxy-Nojirimycin |
| desoxynojirimycin |
| (2R,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol |
| S-GI |
| [2R-(2a,3b,4a,5b)]-2-(Hydroxymethyl)-3,4,5-piperidinetriol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of duvoglustat? |
| A: Molecular weight of duvoglustat is 163.172. |
| Q: What are the downstream products of duvoglustat? |
| A: Related downstream products(CAS) of duvoglustat: 80312-32-9;72432-03-2;72599-27-0;69567-10-8;130539-12-7;128985-16-0;73285-50-4;105265-96-1;138381-83-6;122371-65-7. |
| Q: What are the upstream materials of duvoglustat? |
| A: Related upstream materials(CAS) of duvoglustat: 132198-14-2;75016-28-3;69567-11-9;15218-38-9;81703-56-2;72458-46-9. |
| Q: What is the safety information for duvoglustat? |
| A: Safety information for duvoglustat: S26-S37/39-S24/25. |
| Q: What is the SMILES notation of duvoglustat? |
| A: SMILES notation of duvoglustat is OCC1NCC(O)C(O)C1O. |
| Q: What is the melting point of duvoglustat? |
| A: Melting point of duvoglustat is 195-196°C. |
| Q: What is the boiling point of duvoglustat? |
| A: Boiling point of duvoglustat is 361.1±42.0 °C at 760 mmHg. |
| Q: What is the InChIKey of duvoglustat? |
| A: InChIKey of duvoglustat is LXBIFEVIBLOUGU-UHFFFAOYSA-N. |
| Q: What is the LogP of duvoglustat? |
| A: LogP of duvoglustat is -2.10. |
| Q: What is the CAS number of duvoglustat? |
| A: CAS number of duvoglustat is 19130-96-2. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |
| naturewill |
| Henan Tianfu Chemical Co., Ltd. |