2',3'-Dideoxythymidine
2',3'-Dideoxythymidine structure
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Common Name | 2',3'-Dideoxythymidine | ||
|---|---|---|---|---|
| CAS Number | 3416-05-5 | Molecular Weight | 226.229 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C10H14N2O4 | Melting Point | 155-156 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Melting Point | 155-156 °C(lit.) |
| Molecular Formula | C10H14N2O4 |
| Molecular Weight | 226.229 |
| Exact Mass | 226.095352 |
| PSA | 84.32000 |
| LogP | -0.76 |
| Index of Refraction | 1.552 |
| InChIKey | XKKCQTLDIPIRQD-JGVFFNPUSA-N |
| SMILES | Cc1cn(C2CCC(CO)O2)c(=O)[nH]c1=O |
| Storage condition | 2~8°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | C |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 7 | |
|---|---|
| DownStream 4 | |
CAS#:3056-17-5
CAS#:50-89-5![1-[5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-glycero-pentofuranosyl]thymine Structure](https://image.chemsrc.com/caspic/337/121687-74-9.png)
CAS#:121687-74-9
CAS#:123884-08-2
CAS#:107036-54-4
CAS#:320-98-9
CAS#:18107-18-1
CAS#:7481-89-2
CAS#:1463-10-1![5-(Hydroxymethyl)-1-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furany l]-2,4(1H,3H)-pyrimidinedione structure](https://image.chemsrc.com/caspic/356/132820-97-4.png)
CAS#:132820-97-4
CAS#:120966-81-6This table lists relevant public references with title, journal and publication metadata for this compound.
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Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.
PLoS ONE 10(4) , e0123460, (2015) Ventilator-induced lung injury is a form of acute lung injury that develops in critically ill patients on mechanical ventilation and has a high degree of mortality. Nicotinamide phosphoribosyltransfer... |
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Metabolic drug-drug interaction potential of macrolactin A and 7-O-succinyl macrolactin A assessed by evaluating cytochrome P450 inhibition and induction and UDP-glucuronosyltransferase inhibition in vitro.
Antimicrob. Agents Chemother. 58(9) , 5036-46, (2014) Macrolactin A (MA) and 7-O-succinyl macrolactin A (SMA), polyene macrolides containing a 24-membered lactone ring, show antibiotic effects superior to those of teicoplanin against vancomycin-resistant... |
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Cuboplexes: Topologically Active siRNA Delivery.
ACS Nano 9 , 10214-26, (2015) RNAi technology is currently experiencing a revival due to remarkable improvements in efficacy and viability through oligonucleotide chemical manipulations and/or via their packaging into nanoscale ca... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 1-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione |
| ddT & GM-CSF |
| Thymidine,2',3'-dideoxy |
| 2'-3'-didehydro-2'-3'-dideoxythymidine |
| 1-((2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione |
| MFCD00010570 |
| 2',3'-dideoxy-2',3'-didehydro-thymydine |
| D-3'-deoxythymidine |
| 1-[(2R,5S)-5-(Hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione |
| 5-methyl-2',3'-dideoxyuridine |
| 2',3'-dihydro-3'-deoxythymidine |
| 3'-DEOXYTHYMIDINE |
| Dideoxythymidine |
| 2',3'-Dideoxythymidine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the storage conditions for 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: Storage conditions for 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione: 2~8°C. |
| Q: What is the polar surface area (PSA) of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: Polar surface area (PSA) of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 84.32000. |
| Q: What is the melting point of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: Melting point of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 155-156 °C(lit.). |
| Q: What is the safety information for 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: Safety information for 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione: S22-S24/25. |
| Q: What is the CAS number of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: CAS number of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 3416-05-5. |
| Q: What is the molecular weight of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: Molecular weight of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is 226.229. |
| Q: What is the InChIKey of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: InChIKey of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is XKKCQTLDIPIRQD-JGVFFNPUSA-N. |
| Q: What are the upstream materials of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: Related upstream materials(CAS) of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione: 3056-17-5;50-89-5;121687-74-9;123884-08-2;107036-54-4;320-98-9;18107-18-1. |
| Q: What is the SMILES notation of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: SMILES notation of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is Cc1cn(C2CCC(CO)O2)c(=O)[nH]c1=O. |
| Q: What is the LogP of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione? |
| A: LogP of 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione is -0.76. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Dayang Chem (Hangzhou) Co., Ltd. |