2',3'-Dideoxythymidine
Names
[ CAS No. ]:
3416-05-5
[ Name ]:
2',3'-Dideoxythymidine
[Synonym ]:
1-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
ddT & GM-CSF
Thymidine,2',3'-dideoxy
2'-3'-didehydro-2'-3'-dideoxythymidine
1-((2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
MFCD00010570
2',3'-dideoxy-2',3'-didehydro-thymydine
D-3'-deoxythymidine
1-[(2R,5S)-5-(Hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
5-methyl-2',3'-dideoxyuridine
2',3'-dihydro-3'-deoxythymidine
3'-DEOXYTHYMIDINE
Dideoxythymidine
2',3'-Dideoxythymidine
2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Melting Point ]:
155-156 °C(lit.)
[ Molecular Formula ]:
C10H14N2O4
[ Molecular Weight ]:
226.229
[ Exact Mass ]:
226.095352
[ PSA ]:
84.32000
[ LogP ]:
-0.76
[ Index of Refraction ]:
1.552
[ Storage condition ]:
2~8°C
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
C
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
PLoS ONE 10(4) , e0123460, (2015)
Ventilator-induced lung injury is a form of acute lung injury that develops in critically ill patients on mechanical ventilation and has a high degree of mortality. Nicotinamide phosphoribosyltransfer...
Metabolic drug-drug interaction potential of macrolactin A and 7-O-succinyl macrolactin A assessed by evaluating cytochrome P450 inhibition and induction and UDP-glucuronosyltransferase inhibition in vitro.Antimicrob. Agents Chemother. 58(9) , 5036-46, (2014)
Macrolactin A (MA) and 7-O-succinyl macrolactin A (SMA), polyene macrolides containing a 24-membered lactone ring, show antibiotic effects superior to those of teicoplanin against vancomycin-resistant...
Cuboplexes: Topologically Active siRNA Delivery.ACS Nano 9 , 10214-26, (2015)
RNAi technology is currently experiencing a revival due to remarkable improvements in efficacy and viability through oligonucleotide chemical manipulations and/or via their packaging into nanoscale ca...