1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE structure
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Common Name | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | ||
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| CAS Number | 4235-95-4 | Molecular Weight | 786.113 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C44H84NO8P | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1,2-dioleoyl-sn-glycero-3-phosphocholine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes. |
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| Related Catalog |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C44H84NO8P |
|---|---|
| Molecular Weight | 786.113 |
| Exact Mass | 785.593445 |
| PSA | 121.00000 |
| LogP | 11.97 |
| InChIKey | SNKAWJBJQDLSFF-NVKMUCNASA-N |
| SMILES | CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22 |
| Safety Phrases | 36/37 |
| RIDADR | UN 1888 6 |
| HS Code | 2923900090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~88%
1,2-DIOLEOYL-SN... CAS#:4235-95-4 |
| Literature: Ichihara, Ken'ichi; Iwasaki, Hitomi; Ueda, Kaori; Takizawa, Ryoko; Naito, Hideko; Tomosugi, Mitsuhiro Chemistry and Physics of Lipids, 2005 , vol. 137, # 1-2 p. 94 - 99 |
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1,2-DIOLEOYL-SN... CAS#:4235-95-4 |
| Literature: Tsuboi, Sadao; Takeda, Shinji; Yamasaki, Yasuhisa; Sakai, Takashi; Utaka, Masanori; et al. Chemistry Letters, 1992 , # 8 p. 1417 - 1420 |
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1,2-DIOLEOYL-SN... CAS#:4235-95-4 |
| Literature: Baer et al. Journal of the American Chemical Society, 1956 , vol. 78, p. 232,235 |
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1,2-DIOLEOYL-SN... CAS#:4235-95-4 |
| Literature: Roodsari, Farzaneh S.; Wu, Dongpei; Pum, Gregory S.; Hajdu, Joseph Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 7727 - 7737 |
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1,2-DIOLEOYL-SN... CAS#:4235-95-4 |
| Literature: Tsuboi, Sadao; Takeda, Shinji; Yamasaki, Yasuhisa; Sakai, Takashi; Utaka, Masanori; et al. Chemistry Letters, 1992 , # 8 p. 1417 - 1420 |
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~78%
1,2-DIOLEOYL-SN... CAS#:4235-95-4 |
| Literature: Harris; Marshall; Lee; Siegel; Mcneilly; Yew; Nietupski; Nichols; Cherry; Wan; Jiang; Lane; Rowe; Scheule; Smith; Cheng Phosphorus, Sulfur and Silicon and Related Elements, 1996 , vol. 109, # 1-4 p. 289 - 292 |
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1,2-DIOLEOYL-SN... CAS#:4235-95-4 |
| Literature: Koegl,F. et al. Recueil des Travaux Chimiques des Pays-Bas, 1960 , vol. 79, p. 661 - 674 |
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1,2-DIOLEOYL-SN... CAS#:4235-95-4 |
| Literature: Cubero Robles,E.; de Iongh,H. Recueil des Travaux Chimiques des Pays-Bas, 1967 , vol. 86, p. 762 - 764 |
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~%
1,2-DIOLEOYL-SN... CAS#:4235-95-4 |
| Literature: Harris; Marshall; Lee; Siegel; Mcneilly; Yew; Nietupski; Nichols; Cherry; Wan; Jiang; Lane; Rowe; Scheule; Smith; Cheng Phosphorus, Sulfur and Silicon and Related Elements, 1996 , vol. 109, # 1-4 p. 289 - 292 |
![1,2-DI[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHATE SODIUM SALT structure](https://image.chemsrc.com/caspic/452/108392-02-5.png)
![[(E)-octadec-9-enoyl] (E)-octadec-9-enoate structure](https://image.chemsrc.com/caspic/181/6085-36-5.png)
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
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| DownStream 4 | |
CAS#:4004-05-1
CAS#:108824-18-6This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2923900090 |
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| Summary | 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions.
Biochim. Biophys. Acta 1838(10) , 2615-24, (2014) We have studied the dynamics of Lissamine Rhodamine B dye sensitization-induced oxidation of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) giant unilamellar vesicles (GUVs), where the progression of... |
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Unsaturated lipids protect the integral membrane peptide gramicidin A from singlet oxygen
FEBS Lett. 588(9) , 1590-5, (2014) • Unsaturated lipids protect gramicidin channels from photosensitized inactivation. • Photosensitizer binding to membrane is independent of lipid unsaturation. • Double bonds in lipids reduce gramicid... |
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Antibiotic delivery by liposomes from prokaryotic microorganisms: Similia cum similis works better.
Eur. J. Pharm. Biopharm. 94 , 411-8, (2015) To date the effectiveness of antibiotics is undermined by microbial resistance, threatening public health worldwide. Enhancing the efficacy of the current antibiotic arsenal is an alternative strategy... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Ethanaminium, 2-[[[(2R)-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt |
| EINECS 224-193-8 |
| MFCD00135191 |
| (2R)-2,3-Bis[(9Z)-9-octadecenoyloxy]propyl 2-(trimethylammonio)ethyl phosphate |
| 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE |
| 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine DOPC |
| (R)-2,3-Bis(oleoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate |
| (2R)-2,3-Bis[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: Main uses of 1,2-dioleoyl-sn-glycero-3-phosphocholine: 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes. |
| Q: What is the LogP of 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: LogP of 1,2-dioleoyl-sn-glycero-3-phosphocholine is 11.97. |
| Q: What is the safety information for 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: Safety information for 1,2-dioleoyl-sn-glycero-3-phosphocholine: 36/37. |
| Q: What is the molecular formula of 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: Molecular formula of 1,2-dioleoyl-sn-glycero-3-phosphocholine is C44H84NO8P. |
| Q: What is the polar surface area (PSA) of 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: Polar surface area (PSA) of 1,2-dioleoyl-sn-glycero-3-phosphocholine is 121.00000. |
| Q: What is the SMILES notation of 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: SMILES notation of 1,2-dioleoyl-sn-glycero-3-phosphocholine is CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC. |
| Q: What is the CAS number of 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: CAS number of 1,2-dioleoyl-sn-glycero-3-phosphocholine is 4235-95-4. |
| Q: What are the upstream materials of 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: Related upstream materials(CAS) of 1,2-dioleoyl-sn-glycero-3-phosphocholine: 112-80-1;28319-77-9;24529-88-2;75-50-3;62-49-7;108392-02-5;112-77-6;6085-36-5. |
| Q: What is the English name of 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: The English name of 1,2-dioleoyl-sn-glycero-3-phosphocholine is 1,2-dioleoyl-sn-glycero-3-phosphocholine. |
| Q: What is the molecular weight of 1,2-dioleoyl-sn-glycero-3-phosphocholine? |
| A: Molecular weight of 1,2-dioleoyl-sn-glycero-3-phosphocholine is 786.113. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Shanghai Top Intermediates Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |