1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE structure
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Common Name | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | ||
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| CAS Number | 4235-95-4 | Molecular Weight | 786.113 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C44H84NO8P | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions.
Biochim. Biophys. Acta 1838(10) , 2615-24, (2014) We have studied the dynamics of Lissamine Rhodamine B dye sensitization-induced oxidation of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) giant unilamellar vesicles (GUVs), where the progression of the underlying chemical processes was followed via vesicle... |
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Unsaturated lipids protect the integral membrane peptide gramicidin A from singlet oxygen
FEBS Lett. 588(9) , 1590-5, (2014) • Unsaturated lipids protect gramicidin channels from photosensitized inactivation. • Photosensitizer binding to membrane is independent of lipid unsaturation. • Double bonds in lipids reduce gramicidin inactivation by tert-butyl hydroperoxide. |
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Antibiotic delivery by liposomes from prokaryotic microorganisms: Similia cum similis works better.
Eur. J. Pharm. Biopharm. 94 , 411-8, (2015) To date the effectiveness of antibiotics is undermined by microbial resistance, threatening public health worldwide. Enhancing the efficacy of the current antibiotic arsenal is an alternative strategy. The administration of antimicrobials encapsulated in nano... |
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Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.
Nat. Commun. 5 , 5624, (2014) The earliest molecular events in T-cell recognition have not yet been fully described, and the initial T-cell receptor (TCR)-triggering mechanism remains a subject of controversy. Here, using total internal reflection/Forster resonance energy transfer microsc... |
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The cytolytic activity of vaginolysin strictly depends on cholesterol and is potentiated by human CD59.
Toxins (Basel.) 7(1) , 110-28, (2015) Gardnerella vaginalis produces cytolysin vaginolysin (VLY), which has been suggested to be a contributor to bacterial vaginosis pathogenesis. VLY along with intermedilysin (ILY) from Streptococcus intermedius have been attributed to a group of cholesterol-dep... |
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Size dependent disruption of tethered lipid bilayers by functionalized polystyrene nanoparticles.
Biochim. Biophys. Acta 1848(1 Pt A) , 67-75, (2015) Molecular interactions between engineered nanomaterials (ENM) and biomembranes are not well understood. This study investigated the effects of particle size and surface functional group on polystyrene nanoparticles' (PNPs) potency for biomembrane disruption. ... |
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The p10 FAST protein fusion peptide functions as a cystine noose to induce cholesterol-dependent liposome fusion without liposome tubulation.
Biochim. Biophys. Acta 1848(2) , 408-16, (2014) The reovirus p10 fusion-associated small transmembrane (FAST) proteins are the smallest known membrane fusion proteins, and evolved specifically to mediate cell-cell, rather than virus-cell, membrane fusion. The 36-40-residue ectodomains of avian reovirus (AR... |
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In vitro transport activity of the fully assembled MexAB-OprM efflux pump from Pseudomonas aeruginosa.
Nat. Commun. 6 , 6890, (2015) Antibiotic resistance is a major public health issue and many bacteria responsible for human infections have now developed a variety of antibiotic resistance mechanisms. For instance, Pseudomonas aeruginosa, a disease-causing Gram-negative bacteria, is now re... |
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A novel assay for detecting fusion pore formation: implications for the fusion mechanism.
Biochemistry 52(47) , 8510-7, (2013) Membrane fusion is broadly envisioned as a two- or three-step process proceeding from contacting bilayers through one or two semistable, nonlamellar lipidic intermediate structures to a fusion pore. A true fusion event requires mixing of contents between comp... |
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Effects of fatty acyl chain length, double-bond number and matrix on phosphatidylcholine responses in matrix-assisted laser desorption/ionization on an Orbitrap mass spectrometer.
Rapid Commun. Mass Spectrom. 29 , 2374-84, (2015) Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is used for the fast qualitative and quantitative analysis of phosphatidylcholines (PC). Fatty acyl chain lengths and the number of double bonds (DB) affect relative responses of PC; hen... |