2'-Fluoro-5-methylarabinosyluracil

Modify Date: 2026-07-01 18:33:33

2'-Fluoro-5-methylarabinosyluracil structure	Common Name	2'-Fluoro-5-methylarabinosyluracil
	CAS Number	69256-17-3	Molecular Weight	260.22
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₃FN₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2'-Fluoro-5-methylarabinosyluracil

FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.6±0.1 g/cm3
Molecular Formula	C₁₀H₁₃FN₂O₅
Molecular Weight	260.22
Exact Mass	260.080841
PSA	104.55000
LogP	-0.72
Index of Refraction	1.593
InChIKey	GBBJCSTXCAQSSJ-JVZYCSMKSA-N
SMILES	Cc1cn(C2OC(CO)C(O)C2F)c(=O)[nH]c1=O

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YQ9512600

CHEMICAL NAME :: Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl -

CAS REGISTRY NUMBER :: 69256-17-3

LAST UPDATED :: 198303

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H13-F-N2-O5

MOLECULAR WEIGHT :: 260.25

WISWESSER LINE NOTATION :: T6NVMVJ E1 A- BT5OTJ CF DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 17 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,3957,1982

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code	2934999090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:97614-47-6 3’,5’-Di-O-benz... CAS#:69124-04-5 1-(3-O-Acetyl-5... CAS#:97614-43-2 2-Deoxy-2-fluor... CAS#:97614-44-3 2-Deoxy-2-fluor...
CAS#:554-01-8 5-METHYLCYTOSINE CAS#:56632-81-6 1,3-di-O-acetyl... CAS#:84025-00-3 1,3-di-O-acetyl... CAS#:83966-95-4 1-(3-O-acetyl-5...
CAS#:65-71-4 Thymine CAS#:7288-28-0 bis(o-trimethyl...
DownStream 6
CAS#:105281-19-4 1-[(2R,3S,4R,5S... CAS#:144822-48-0 1-[5-O-[Bis(4-m... CAS#:40615-39-2 5'-O-Dimethoxyt... CAS#:128114-99-8 Trityl-lyxofura...
CAS#:132776-19-3 Anhydro nucleoside CAS#:132776-20-6 [(2R,3R,4R,5R)-...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: Antiherpetic activity against HSV-1
Source: ChEMBL
Target: Human alphaherpesvirus 1
External Id: CHEMBL883993

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: In vitro inhibitory activity against L1212/0 cell line
Source: ChEMBL
Target: L1210
External Id: CHEMBL709287

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluracil

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the SMILES notation of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil?

A: SMILES notation of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil is Cc1cn(C2OC(CO)C(O)C2F)c(=O)[nH]c1=O.

Q: What is the molecular formula of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil?

A: Molecular formula of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil is C10H13FN2O5.

Q: What is the InChIKey of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil?

A: InChIKey of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil is GBBJCSTXCAQSSJ-JVZYCSMKSA-N.

Q: What is the polar surface area (PSA) of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil?

A: Polar surface area (PSA) of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil is 104.55000.

Q: What are the downstream products of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil?

A: Related downstream products(CAS) of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil: 105281-19-4;144822-48-0;40615-39-2;128114-99-8;132776-19-3;132776-20-6.

Q: What is the LogP of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil?

A: LogP of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil is -0.72.

Q: What is the CAS number of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil?

A: CAS number of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil is 69256-17-3.

Q: What are the upstream materials of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil?

A: Related upstream materials(CAS) of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil: 97614-47-6;69124-04-5;97614-43-2;97614-44-3;554-01-8;56632-81-6;84025-00-3;83966-95-4;65-71-4;7288-28-0.

Q: What is the English name of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil?

A: The English name of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil is 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil.

Q: What English synonyms does 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil have?

A: English synonyms of 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil: 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluracil, 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2'-Fluoro-5-methylarabinosyluracil
Price: Check
Purity: 98.21%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2'-Fluoro-5-methylarabinosyluracil
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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2'-Fluoro-5-methylarabinosyluracil

Use of 2'-Fluoro-5-methylarabinosyluracil

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