Homovanillic acid

Modify Date: 2025-08-20 19:57:08

Homovanillic acid Structure
Homovanillic acid structure
Common Name Homovanillic acid
CAS Number 306-08-1 Molecular Weight 182.173
Density 1.3±0.1 g/cm3 Boiling Point 368.7±27.0 °C at 760 mmHg
Molecular Formula C9H10O4 Melting Point 142-145 °C(lit.)
MSDS Chinese USA Flash Point 151.9±17.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Homovanillic acid


Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

 Names

Name homovanillic acid
Synonym More Synonyms

 Homovanillic acid Biological Activity

Description Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
Related Catalog
Target

Human Endogenous Metabolite

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 368.7±27.0 °C at 760 mmHg
Melting Point 142-145 °C(lit.)
Molecular Formula C9H10O4
Molecular Weight 182.173
Flash Point 151.9±17.2 °C
Exact Mass 182.057907
PSA 66.76000
LogP 0.47
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.573
InChIKey QRMZSPFSDQBLIX-UHFFFAOYSA-N
SMILES COc1cc(CC(=O)O)ccc1O
Storage condition Store at RT.
Water Solubility soluble

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918990090

 Synthetic Route

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles207

More Articles
Permeation of Dopamine Sulfate through the Blood-Brain Barrier.

PLoS ONE 10 , e0133904, (2015)

Dopamine sulfate (DA-3- and DA-4-S) have been determined in the human brain, but it is unclear whether they are locally formed in the central nervous system (CNS), or transported into the CNS from per...

Toxicity of copper on isolated liver mitochondria: impairment at complexes I, II, and IV leads to increased ROS production.

Cell Biochem. Biophys. 70(1) , 367-81, (2014)

Oxidative damage has been implicated in disorders associated with abnormal copper metabolism and also Cu(2+) overloading states. Besides, mitochondria are one of the most important targets for Cu(2+),...

Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator.

J. Pharmacol. Exp. Ther. 350(3) , 589-604, (2014)

Brexpiprazole (OPC-34712, 7-{4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy}quinolin-2(1H)-one) is a novel drug candidate in clinical development for psychiatric disorders with high affinity for ser...

 Homovanillic acidBioassay

View more

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint...
Source: Broad Institute
Target: N/A
External Id: 2084-01_Activator_SinglePoint_HTS_Activity
Name: Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberc...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: GDH-TPI_INH_ABS_1536_1X%INH CSRUN
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 Synonyms

Homovanillinic acid
2-(4-Hydroxy-3-methoxyphenyl)acetic acid
HOMORANILLIC ACID
EINECS 206-176-7
4-Hydroxy-3-methoxy-a-toluic Acid
2-(4-hydroxy-3-methoxyphenyl)ethanoic acid
RARECHEM AL BO 0135
Vanillacetic Acid
Vanilacetic acid
(4-Hydroxy-3-methoxyphenyl)acetic acid
3-methoxy-4-hydroxyphenylacetic acid
HVA
MFCD00004350
4-Hydroxy-3-methoxyphenylacetic Acid
Homovanillic acid
Homovanillate
Homovaniuic acid
HomovanillicAcid
Methoxy-4-Hydroxyphenylacetate
3-methoxy-4-hydroxy-phenylacetic acid
Homovanilic acid
4-Hydroxy-3-methoxyphenylacetic acid HVA
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