e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Journal of the American Chemical Society

Naphthoquinone antimalarials. XXIII. Bz-substituted derivatives

LF Fieser, RH Brown

Index: Fieser; Brown Journal of the American Chemical Society, 1949 , vol. 71, p. 3615

Full Text: HTML

Citation Number: 13

Abstract

VI11 T VI\'I1 brine would suggest the possibility of a more favor-droquinone triacetates, each of which was conable result from the introduction of@-methoxy or verted into the corresponding hydroxychloro-P-chloro substituents into the aromatic ring, sev- naphthoquinone. One of these was identified as era1 new compounds of this type have been examined. 0

methyl iodide Structure

~%

1,4-Naphthalenedione,2-methoxy-3-methyl- Structure

1,4-Naphthalene...

Diethyl ether Structure

Peroxide, diacetyl Structure

Peroxide, diacetyl

2-Chloro-1,4-naphthoquinone Structure

2-Chloro-1,4-na...

acetic acid Structure

~%

Detail

2,3-Dichlor-1,4-naphthochinone Structure

2,3-Dichlor-1,4...

2-Naphthalenethiol Structure

2-Naphthalenethiol

~%

2,3-bis(naphthalen-2-ylsulfanyl)naphthalene-1,4-dione Structure

2,3-bis(naphtha...

1,4-Naphthalenediol,6-chloro-5,8-dihydro- Structure

1,4-Naphthalene...

~%

6-chloronaphthalene-1,4-dione Structure

6-chloronaphtha...

2,3-Dichlor-1,4-naphthochinone Structure

2,3-Dichlor-1,4...

1-Propanethiol Structure

~%

2-chloro-3-propylsulfanylnaphthalene-1,4-dione Structure

2-chloro-3-prop...

1-Propanethiol Structure

2-Chloro-1,4-naphthoquinone Structure

2-Chloro-1,4-na...

~%

2-chloro-3-propylsulfanylnaphthalene-1,4-dione Structure

2-chloro-3-prop...

2-Chloro-1,4-naphthoquinone Structure

2-Chloro-1,4-na...

Sodium Methylate Structure

Sodium Methylate

~%

Lawsone methyl ether Structure

Lawsone methyl ether

Menadione Structure

benzylthiol Structure

~%

1,4-Naphthalenedione,2-methyl-3-[(phenylmethyl)thio]- Structure

1,4-Naphthalene...

2,3-Dichlor-1,4-naphthochinone Structure

2,3-Dichlor-1,4...

butanethiol Structure

~%

2-butylsulfanyl-3-chloronaphthalene-1,4-dione Structure

2-butylsulfanyl...

butanethiol Structure

2-Chloro-1,4-naphthoquinone Structure

2-Chloro-1,4-na...

~%

2-butylsulfanyl-3-chloronaphthalene-1,4-dione Structure

2-butylsulfanyl...

2,3-Dichlor-1,4-naphthochinone Structure

2,3-Dichlor-1,4...

Ethanethiol Structure

~%

2,3-bis(ethylsulfanyl)naphthalene-1,4-dione Structure

2,3-bis(ethylsu...

2-Naphthalenethiol Structure

2-Naphthalenethiol

1,4-naphthoquinone Structure

1,4-naphthoquinone

~%

2-naphthalen-2-ylsulfanylnaphthalene-1,4-dione Structure

2-naphthalen-2-...

3-ethyl-1-oxo-1,2,3,4-tetrahydronaphthalene Structure

3-ethyl-1-oxo-1...

~%

1,4-Naphthalenedione,2-ethyl-3-hydroxy- Structure

1,4-Naphthalene...

Menadione Structure

Ethanethiol Structure

~%

2-(Ethylthio)-3-methyl-1,4-naphthoquinone Structure

2-(Ethylthio)-3...

2,3-Dichlor-1,4-naphthochinone Structure

2,3-Dichlor-1,4...

P-toluenethiol Structure

~%

1,4-Naphthalenedione,2,3-bis[(4-methylphenyl)thio]- Structure

1,4-Naphthalene...

Menadione Structure

2-Propanethiol Structure

~%

2-methyl-3-propan-2-ylsulfanylnaphthalene-1,4-dione Structure

2-methyl-3-prop...

benzylthiol Structure

1,4-naphthoquinone Structure

1,4-naphthoquinone

~%

2-benzylsulfanylnaphthalene-1,4-dione Structure

2-benzylsulfany...

Peroxide, diacetyl Structure

Peroxide, diacetyl

2-Chloro-1,4-naphthoquinone Structure

2-Chloro-1,4-na...

~%

2-chloro-3-methylnaphthalene-1,4-dione Structure

2-chloro-3-meth...