Organic Letters 2009-08-06

New one-pot synthesis of (E)-beta-aryl vinyl halides from styrenes.

Piotr Pawluć, Grzegorz Hreczycho, Justyna Szudkowska, Maciej Kubicki, Bogdan Marciniec

Index: Org. Lett. 11(15) , 3390-3, (2009)

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Abstract

A new, efficient protocol for the highly stereoselective one-pot synthesis of (E)-beta-aryl vinyl iodides and (E)-beta-aryl vinyl bromides from styrenes based on sequential ruthenium-catalyzed silylative coupling-N-halosuccinimide-mediated halodesilylation reactions is reported.