Chemico-Biological Interactions 2013-05-25

Protective effect of crocin on diazinon induced cardiotoxicity in rats in subchronic exposure

Bibi Marjan Razavi, Hossein Hosseinzadeh, Ahmad Reza Movassaghi, Mohsen Imenshahidi, Khalil Abnous

Index: Chem. Biol. Interact. 203(3) , 547-55, (2013)

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Abstract

Highlights • DZN increased MDA level in the heart of rat and elevated CK-MB activity. • DZN induced histopathological damages in the heart of rat. • DZN induced mitochondria mediated apoptosis in the heart of rat. • Crocin attenuated all toxic effects induced by DZN.