PLoS ONE 2015-01-01

SBA-15 Mesoporous Silica Modified with Gallic Acid and Evaluation of Its Cytotoxic Activity.

Dawid Lewandowski, Piotr Ruszkowski, Anita Pińska, Grzegorz Schroeder, Joanna Kurczewska

Index: PLoS ONE 10 , e0132541, (2015)

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Abstract

Gallic acid has been covalently conjugated to SBA-15 mesoporous silica surface through different linkers. Cytotoxic activity of the hybrid organic-inorganic systems against HeLa and KB cell lines has been analyzed. Up to 67% of HeLa or KB tumor cells growth inhibition has been achieved at low silica concentration used (10 μg mL(-1)).