e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synlett
Synthesis of Functionalized 2-Arylthiophenes with Triarylbismuths as Atom-Efficient Multicoupling Organometallic Nucleophiles under Palladium Catalysis
MLN Rao, D Banerjee, RJ Dhanorkar
Index: Rao, Maddali L. N.; Banerjee, Debasis; Dhanorkar, Ritesh J. Synlett, 2011 , # 9 p. 1324 - 1330
Abstract Atom-efficient cross-coupling reactions of functionalized 2-bromo-and 2- iodothiophenes have been demonstrated using triarylbismuths as atom-efficient multicoupling organometallic nucleophiles under palladium-catalyzed conditions. These couplings with various functionalized triarylbismuths proceeded smoothly to afford the corresponding functionalized 2-arylthiophenes in high yields.
![1-[5-(4-methylphenyl)thiophen-2-yl]ethanone Structure](https://image.chemsrc.com/caspic/269/51335-91-2.png)
![Ethanone, 1,1'-[2,2'-bithiophene]-5,5'-diylbis Structure](https://image.chemsrc.com/caspic/248/18494-73-0.png)
![[2,2’]bithiophenyl-5,5'-dicarbaldehyde Structure](https://image.chemsrc.com/caspic/085/32364-72-0.png)
![1-[5-(4-methoxyphenyl)thiophene-2-yl]ethanone Structure](https://image.chemsrc.com/caspic/066/13918-67-7.png)
![1-{5-[3-(Trifluoromethyl)Phenyl]-2-thienyl}ethanon Structure](https://image.chemsrc.com/caspic/271/893735-18-7.png)
![1-[5-(3-chlorophenyl)thiophen-2-yl]ethanone Structure](https://image.chemsrc.com/caspic/082/855609-52-8.png)