Tetrahedron letters

A simple method for the synthesis of some 1, 2-diazocines

MJ Haddadin, BJ Agha, MS Salka

Index: Haddadin, Makhluf J.; Agha, Bushra J.; Salka, M. Samer Tetrahedron Letters, 1984 , vol. 25, # 24 p. 2577 - 2580

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Citation Number: 16

Abstract

Abstract Cyclobutanone reacts with diphenyl-1, 2, 4, 5-tetrazine, in alcoholic base and in diethylamine, to give 3, 8-diphenyl-6, 7-dihydro-1, 2-diazocin-4 (5H)-one (5) and 4- diethylamino-3, 8-diphenyl-6, 7-dihydro-1, 2-diazocine (8) respectively. With diethylamine the tetrazine yields 3, 6-diphenylpyridazine.