Unexpected C–C Bond Cleavage: A Route to 3, 6-Diarylpyridazines and 6-Arylpyridazin-3-ones from 1, 3-Dicarbonyl Compounds and Methyl Ketones

Q Gao, Y Zhu, M Lian, M Liu, J Yuan…

Index: Gao, Qinghe; Zhu, Yanping; Lian, Mi; Liu, Meicai; Yuan, Jingjing; Wu, Anxin; Yin, Guodong Journal of Organic Chemistry, 2012 , vol. 77, # 21 p. 9865 - 9870,6

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Citation Number: 27

Abstract

An unexpected C–C bond cleavage has been revealed in the absence of metal. This observation has been exploited to develop an efficient approach toward 3, 6- diarylpyridazines and 6-arylpyridazin-3-ones from simple and commercially available 1, 3- dicarbonyl compounds and methyl ketones.