Metal??Free Oxidative Fluorination of Phenols with [18F] Fluoride

…, M Tredwell, L Li, S Verhoog, M Hopkinson…

Index: Gao, Zhanghua; Lim, Yee Hwee; Tredwell, Matthew; Li, Lei; Verhoog, Stefan; Hopkinson, Matthew; Kaluza, Wojciech; Collier, Thomas Lee; Passchier, Jan; Huiban, Mickael; Gouverneur, Veronique Angewandte Chemie - International Edition, 2012 , vol. 51, # 27 p. 6733 - 6737

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Citation Number: 57

Abstract

Positron emission tomography (PET) is a molecular imaging technique that captures functional or phenotypic changes associated with pathology.[1] This research field is currently fuelled by the need for conceptually new 18F-radiolabeling methods to satisfy clinical demand.[2] 18F-labeled aryl derivatives are highly sought after in the context of both drug and radiotracer development because of their advantageous metabolic profile for in ...