4-Fluoro-3-methylphenol

Modify Date: 2024-01-02 12:09:05

4-Fluoro-3-methylphenol Structure
4-Fluoro-3-methylphenol structure
Common Name 4-Fluoro-3-methylphenol
CAS Number 452-70-0 Molecular Weight 126.128
Density 1.2±0.1 g/cm3 Boiling Point 205.8±20.0 °C at 760 mmHg
Molecular Formula C7H7FO Melting Point 32 °C(lit.)
MSDS USA Flash Point 96.7±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Fluoro-3-methylphenol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 205.8±20.0 °C at 760 mmHg
Melting Point 32 °C(lit.)
Molecular Formula C7H7FO
Molecular Weight 126.128
Flash Point 96.7±0.0 °C
Exact Mass 126.048096
PSA 20.23000
LogP 2.23
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.520

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR 1759
WGK Germany 3
HS Code 2908199090

 Synthetic Route

~71%

4-Fluoro-3-methylphenol Structure

4-Fluoro-3-meth...

CAS#:452-70-0

Literature: Samant, Bhupesh S.; Bhagwat, Sunil S. Applied Catalysis A: General, 2011 , vol. 394, # 1-2 p. 191 - 194

~57%

4-Fluoro-3-methylphenol Structure

4-Fluoro-3-meth...

CAS#:452-70-0

Literature: Singh, Sukhjinder; DesMarteau, Darryl D.; Zuberi, Sharique S.; Witz, Michael; Huang, Hsu-Nan Journal of the American Chemical Society, 1987 , vol. 109, # 23 p. 7194 - 7196

~37%

4-Fluoro-3-methylphenol Structure

4-Fluoro-3-meth...

CAS#:452-70-0

Literature: Gao, Zhanghua; Lim, Yee Hwee; Tredwell, Matthew; Li, Lei; Verhoog, Stefan; Hopkinson, Matthew; Kaluza, Wojciech; Collier, Thomas Lee; Passchier, Jan; Huiban, Mickael; Gouverneur, Veronique Angewandte Chemie - International Edition, 2012 , vol. 51, # 27 p. 6733 - 6737

~89%

4-Fluoro-3-methylphenol Structure

4-Fluoro-3-meth...

CAS#:452-70-0

Literature: Yoneda; Fukuhara Tetrahedron, 1996 , vol. 52, # 1 p. 23 - 36

~%

4-Fluoro-3-methylphenol Structure

4-Fluoro-3-meth...

CAS#:452-70-0

Literature: Gao, Zhanghua; Lim, Yee Hwee; Tredwell, Matthew; Li, Lei; Verhoog, Stefan; Hopkinson, Matthew; Kaluza, Wojciech; Collier, Thomas Lee; Passchier, Jan; Huiban, Mickael; Gouverneur, Veronique Angewandte Chemie - International Edition, 2012 , vol. 51, # 27 p. 6733 - 6737

~%

4-Fluoro-3-methylphenol Structure

4-Fluoro-3-meth...

CAS#:452-70-0

Literature: Dat-Xuong,N. et al. Chimica Therapeutica, 1967 , vol. 2, p. 53 - 56

~%

4-Fluoro-3-methylphenol Structure

4-Fluoro-3-meth...

CAS#:452-70-0

Literature: Dat-Xuong,N. et al. Chimica Therapeutica, 1967 , vol. 2, p. 53 - 56

 Customs

HS Code 2908199090
Summary HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

 Articles2

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Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase.

Bioorg. Med. Chem. 15 , 7638-46, (2007)

The naphthoquinone 7-methyljuglone (5-hydroxy-7-methyl-1,4-naphthoquinone) has previously been isolated and identified as an active component of root extracts of Euclea natalensis which displays antit...

Use of Fluorinated Compounds To Detect Aromatic Metabolites from m-Cresol in a Methanogenic Consortium: Evidence for a Demethylation Reaction.

Appl. Environ. Microbiol. 59(7) , 2229-38, (1993)

Anaerobic sewage sludge was used to enrich a methanogenic m-cresol-degrading consortium. 6-Fluoro-3-methylphenol was synthesized and added to subcultures of the consortium with m-cresol. This caused t...

 Synonyms

4-Fluoro-m-cresol
Phenol, 4-fluoro-3-methyl-
MFCD00042296
4-Fluor-3-methyl-phenol
4-fluoro-3-methyl-phenol
3-methyl-4-fluorophenol
4-Fluoro-3-methylphenol
QR DF C1
4-Fluoro-3-me-phenol
2-Fluoro-5-hydroxytoluene
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