4-cumylphenol

Modify Date: 2025-08-24 17:58:11

4-cumylphenol structure	Common Name	4-cumylphenol
	CAS Number	599-64-4	Molecular Weight	212.28700
	Density	1,115 g/cm3	Boiling Point	335 °C
	Molecular Formula	C₁₅H₁₆O	Melting Point	72-75 °C
	MSDS	Chinese USA	Flash Point	160 °C
	Symbol	GHS07	Signal Word	Warning

Use of 4-cumylphenol

4-Cumylphenol is a polycarbonate chain terminator. 4-Cumylphenol is widely used as a material for polycarbonate plastics, surfactants, fungicides and preservatives. 4-Cumylphenol also induces lipid accumulation in mouse adipocytes[1][2][3].

Name	4-cumylphenol
Synonym	More Synonyms

Description	4-Cumylphenol is a polycarbonate chain terminator. 4-Cumylphenol is widely used as a material for polycarbonate plastics, surfactants, fungicides and preservatives. 4-Cumylphenol also induces lipid accumulation in mouse adipocytes[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	4-Cumylphenol (1, 5, 10, 20, 40 µM; 6 days) increase lipid accumulation in 3 T3-L1 cells[3]. Cell Viability Assay[3] Cell Line: 3 T3-L1 cells Concentration: 1, 5, 10, 20, 40 µM Incubation Time: 6 days Result: Increase lipid accumulation, which peaked at10 μM with a 204% increase.
References	[1]. Yue W, et al. Biodegradation of bisphenol-A polycarbonate plastic by Pseudoxanthomonas sp. strain NyZ600. J Hazard Mater. 2021 Aug 15;416:125775. [2]. Chiha M, et al. Sonolytic degradation of endocrine disrupting chemical 4-cumylphenol in water. Ultrason Sonochem. 2011 Sep;18(5):943-50. [3]. Ramskov Tetzlaff CN, Svingen T, et al. Bisphenols B, E, F, and S and 4-cumylphenol induce lipid accumulation in mouse adipocytes similarly to bisphenol A. Environ Toxicol. 2020 May;35(5):543-552.

Density	1,115 g/cm3
Boiling Point	335 °C
Melting Point	72-75 °C
Molecular Formula	C₁₅H₁₆O
Molecular Weight	212.28700
Flash Point	160 °C
Exact Mass	212.12000
PSA	20.23000
LogP	3.71810
Index of Refraction	1.587
Stability	Stable. Incompatible with oxidizing agents, acid chlorides, acid anhydrides. Combustible.

4-cumylphenol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL1942450

CHEMICAL NAME :: Phenol, p-(alpha,alpha-dimethylbenzyl)-

CAS REGISTRY NUMBER :: 599-64-4

BEILSTEIN REFERENCE NO. :: 1870517

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H16-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 335 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 12(12),44,1968

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S24/25-S37/39-S26
RIDADR	NONH for all modes of transport
RTECS	SL1942450

Precursor 9
CAS#:80-05-7 bisphenol A CAS#:98-83-9 α-methylstyrene CAS#:108-95-2 Phenol CAS#:617-94-7 α-Cumyl alcohol
CAS#:6623-93-4 Benzene,1-metho... CAS#:934-53-2 Alpha,alpha-dim... CAS#:13139-86-1 4-Anisylmagnesi... CAS#:98-82-8 Cumene
CAS#:80-15-9 Cumyl hydroperoxide
DownStream 9
CAS#:20056-52-4 4-(2-phenylprop... CAS#:371-41-5 4-Fluorophenol CAS#:76953-23-6 p-cumylphenyl n... CAS#:628-13-7 Pyridine chlorh...
CAS#:24133-73-1 Phenol,4-(1-met... CAS#:24133-64-0 2-nitro-4-(2-ph... CAS#:83482-57-9 4-[4-(2-Phenyl-... CAS#:33524-49-1 carbonic acid,4...
CAS#:119-36-8 Methyl salicylate

Degradation and toxicity reduction of the endocrine disruptors nonylphenol, 4-tert-octylphenol and 4-cumylphenol by the non-ligninolytic fungus Umbelopsis isabellina.

Bioresour. Technol. 200 , 223-9, (2015)

Nonylphenol (NP), 4-tert-octylphenol (4-t-OP) and 4-cumylphenol (4-CP) are pollutants that are known as endocrine disruptors mainly due to their estrogen-mimicking activity. These phenolic substances ...

Occurrence, removal, and fate of progestogens, androgens, estrogens, and phenols in six sewage treatment plants around Dianchi Lake in China.

Environ. Sci. Pollut. Res. Int. 21(22) , 12898-908, (2014)

The occurrence and behavior of endocrine disrupting chemicals (EDCs) in sewage treatment plants (STPs), especially estrogens and phenols, have been closely concerned in previous studies. However, the ...

Double salts of ionic-liquid-based surfactants in microextraction: application of their mixed hemimicelles as novel sorbents in magnetic-assisted micro-dispersive solid-phase extraction for the determination of phenols.

Anal. Bioanal. Chem 407 , 8753-64, (2015)

The use of mixed hemimicelles of ionic liquid (IL)-based surfactants in a magnetic-based micro-dispersive solid-phase extraction (m-μdSPE) approach is described. Not only is the symmetric monocationic...

P-CUMYLPHENOL

AURORA 4778

paracumilphenol

PARA-CUMYLPHENOL

PCP

Cumyl phenol

EINECS 209-968-0

MFCD00002365

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4-cumylphenol
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 4-cumylphenol
Price: ￥658.0/500g ￥188.0/100g
Purity: 99.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Cumylphenol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Phenol,4-(1-methyl-1-phenylethyl)-,cas:599-64-4
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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4-cumylphenol

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