2-Amido-8-methoxytetralins: a series of nonindolic melatonin-like agents

S Copinga, PG Tepper, CJ Grol, AS Horn…

Index: Copinga, Swier; Tepper, Pieter G.; Grol, Cor J.; Horn, Alan S.; Dubocovich, Margarita L. Journal of Medicinal Chemistry, 1993 , vol. 36, # 20 p. 2891 - 2898

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Citation Number: 91

Abstract

A series of unsubstituted and methoxy-substituted 2-amidotetralins (4a-q) was prepared and evaluated for their ability to compete for 2-[lBI] iodornelatonin binding to chicken retinal membranes and for their potency to inhibit the calcium-dependent release of [3H] ...

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