5-HT1A modulator 2 hydrochloride

Modify Date: 2024-01-02 16:25:15

5-HT1A modulator 2 hydrochloride Structure
5-HT1A modulator 2 hydrochloride structure
Common Name 5-HT1A modulator 2 hydrochloride
CAS Number 3880-76-0 Molecular Weight 213.704
Density N/A Boiling Point 341.2ºC at 760mmHg
Molecular Formula C11H16ClNO Melting Point N/A
MSDS N/A Flash Point 160.2ºC

 Use of 5-HT1A modulator 2 hydrochloride


5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT (HY-112061), is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1].

 Names

Name 2-amino-8-methoxy-1,2,3,4-tetrahydronaphthalene hcl
Synonym More Synonyms

 5-HT1A modulator 2 hydrochloride Biological Activity

Description 5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT (HY-112061), is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1].
Related Catalog
Target

Ki: 53 nM (5-HT1A)[1]

In Vitro 5-HT1A modulator 2 hydrochloride (compound 3) binds to 5-HT1A with a Ki of 53 nM[1].
References

[1]. Naiman, N.,et al. 2-(Alkylamino)tetralin derivatives: interaction with 5-HT1A serotonin binding sites. Journal of Medicinal Chemistry, 1989;32(1), 253–256.

 Chemical & Physical Properties

Boiling Point 341.2ºC at 760mmHg
Molecular Formula C11H16ClNO
Molecular Weight 213.704
Flash Point 160.2ºC
Exact Mass 213.092041
PSA 35.25000
LogP 3.01350

 Safety Information

HS Code 2922299090

 Synthetic Route

~71%

5-HT1A modulator 2 hydrochloride Structure

5-HT1A modulato...

CAS#:3880-76-0

Literature: Langlois; Gaudy Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734

~%

5-HT1A modulator 2 hydrochloride Structure

5-HT1A modulato...

CAS#:3880-76-0

Literature: Langlois; Gaudy Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734

~%

5-HT1A modulator 2 hydrochloride Structure

5-HT1A modulato...

CAS#:3880-76-0

Literature: Langlois; Gaudy Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734

~%

5-HT1A modulator 2 hydrochloride Structure

5-HT1A modulato...

CAS#:3880-76-0

Literature: Langlois; Gaudy Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734

~%

5-HT1A modulator 2 hydrochloride Structure

5-HT1A modulato...

CAS#:3880-76-0

Literature: Langlois; Gaudy Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734

~%

5-HT1A modulator 2 hydrochloride Structure

5-HT1A modulato...

CAS#:3880-76-0

Literature: Langlois; Gaudy Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734

~%

5-HT1A modulator 2 hydrochloride Structure

5-HT1A modulato...

CAS#:3880-76-0

Literature: Langlois; Gaudy Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734

~%

5-HT1A modulator 2 hydrochloride Structure

5-HT1A modulato...

CAS#:3880-76-0

Literature: Langlois; Gaudy Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734

 Customs

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine hydrochloride
2-Naphthalenamine, 1,2,3,4-tetrahydro-8-methoxy-, hydrochloride (1:1)
1,2,3,4-Tetrahydro-8-methoxy-2-naphthalenamine hydrochloride
8-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (1:1)
8-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride (1:1)
8-methoxy-2-amino tetralin hydrochloride
2-Amino-8-methoxytetralin hydrochloride
2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalenehydrochloride
dl-1,2,3,4-tetrahydro-8-methoxy-2-naphthalenamine hydrochloride
8-Methoxy-1,2,3,4-tetrahydronaphthalen-2-aMine
8-Methoxy-(2R)-2-amino-1,2,3,4-tetrahydronaphthalene hydrochloride
8-Methoxy-2-amino-1,2,3,4-tetrahydronaphthalene hydrochloride
8-methoxy-1,2,3,4-tetrahydro naphthalen-2-amine