e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

The Journal of Organic Chemistry

4-(5-Nitro-2-furyl) thiazoles1a

WR SHERMAN, DE DICKSON

Index: Sherman,W.R.; Dickson,D.E. Journal of Organic Chemistry, 1962 , vol. 27, p. 1351 - 1355

Full Text: HTML

Citation Number: 33

Abstract

Bromination of the 2-aminonitrofurylthiazole IVc and its acetyl derivative V gave monobromo compounds. These are considered to be the 5-bromothiazoles because of the inactivity of the nitrofuran ring toward bromination and the ease with which aminothiazoles with an unoccupied 5-position undergo halogenati~ n.~ Acetylation of 2-amino-5-bromo-4-(5-nitro-2- furyl) thiazole (VIa) provided an alternate route to the acetyl bromo compound VIb and ...

bromomethyl 5-nitro-furan-2-yl ketone Structure

bromomethyl 5-n...

thiourea Structure

~%

4-(5-nitrofuran-2-yl)-1,3-thiazol-2-amine Structure

4-(5-nitrofuran...

bromomethyl 5-nitro-furan-2-yl ketone Structure

bromomethyl 5-n...

Acetone thiosemicarbazone Structure

Acetone thiosem...

~%

2-(2-ISOPROPYLIDENEHYDRAZINO)-4-(5-NITRO-2-FURYL)THIAZOLE Structure

2-(2-ISOPROPYLI...

bromomethyl 5-nitro-furan-2-yl ketone Structure

bromomethyl 5-n...

Phenylthiocarbamide Structure

Phenylthiocarbamide

~%

2-Thiazolamine,4-(5-nitro-2-furanyl)-N-phenyl- Structure

2-Thiazolamine,...

bromomethyl 5-nitro-furan-2-yl ketone Structure

bromomethyl 5-n...

~%

Thiazole,2-hydrazinyl-4-(5-nitro-2-furanyl)- Structure

Thiazole,2-hydr...

2-(2-ISOPROPYLIDENEHYDRAZINO)-4-(5-NITRO-2-FURYL)THIAZOLE Structure

2-(2-ISOPROPYLI...

~%

Thiazole,2-hydrazinyl-4-(5-nitro-2-furanyl)- Structure

Thiazole,2-hydr...

bromomethyl 5-nitro-furan-2-yl ketone Structure

bromomethyl 5-n...

Thioformamide Structure

~%

4-(5-nitro-2-furyl)thiazole Structure

4-(5-nitro-2-fu...

bromomethyl 5-nitro-furan-2-yl ketone Structure

bromomethyl 5-n...

Thioacetamide Structure

~%

2-METHYL-4-(5-NITRO-2-FURYL)THIAZOLE Structure

2-METHYL-4-(5-N...

bromomethyl 5-nitro-furan-2-yl ketone Structure

bromomethyl 5-n...

~%

N-acetyl-N-[4-(5-nitro-2-furyl)-1,3-thiazol-2-yl]acetohydrazide Structure

N-acetyl-N-[4-(...

2-(2-ISOPROPYLIDENEHYDRAZINO)-4-(5-NITRO-2-FURYL)THIAZOLE Structure

2-(2-ISOPROPYLI...

~%

N-acetyl-N-[4-(5-nitro-2-furyl)-1,3-thiazol-2-yl]acetohydrazide Structure

N-acetyl-N-[4-(...

Ethanoic anhydride Structure

Ethanoic anhydride

Thiazole,2-hydrazinyl-4-(5-nitro-2-furanyl)- Structure

Thiazole,2-hydr...

~%

N-acetyl-N-[4-(5-nitro-2-furyl)-1,3-thiazol-2-yl]acetohydrazide Structure

N-acetyl-N-[4-(...

bromomethyl 5-nitro-furan-2-yl ketone Structure

bromomethyl 5-n...

~%

Formic acid,2-[4-(5-nitro-2-furanyl)-2-thiazolyl]hydrazide Structure

Formic acid,2-[...

2-(2-ISOPROPYLIDENEHYDRAZINO)-4-(5-NITRO-2-FURYL)THIAZOLE Structure

2-(2-ISOPROPYLI...

~%

Formic acid,2-[4-(5-nitro-2-furanyl)-2-thiazolyl]hydrazide Structure

Formic acid,2-[...

Formic Acid Structure

2-(2-ISOPROPYLIDENEHYDRAZINO)-4-(5-NITRO-2-FURYL)THIAZOLE Structure

2-(2-ISOPROPYLI...

~%

Formic acid,2-[4-(5-nitro-2-furanyl)-2-thiazolyl]hydrazide Structure

Formic acid,2-[...

Formic Acid Structure

Thiazole,2-hydrazinyl-4-(5-nitro-2-furanyl)- Structure

Thiazole,2-hydr...

~%

Formic acid,2-[4-(5-nitro-2-furanyl)-2-thiazolyl]hydrazide Structure

Formic acid,2-[...

furothiazole Structure

~%

N-[5-bromo-4-(5-nitro-2-furyl)-1,3-thiazol-2-yl]acetamide Structure

N-[5-bromo-4-(5...

N/A Structure

~%

N-[5-bromo-4-(5-nitro-2-furyl)-1,3-thiazol-2-yl]acetamide Structure

N-[5-bromo-4-(5...

Ethanoic anhydride Structure

Ethanoic anhydride

N/A Structure

~%

furothiazole Structure

Thiocyanic acid,2-(5-nitro-2-furanyl)-2-oxoethyl ester Structure

Thiocyanic acid...

~%

Thiazole, 2-chloro-4-(5-nitro-2-furanyl)- (9CI) Structure

Thiazole, 2-chl...