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The Journal of Organic Chemistry

4-(5-Nitro-2-furyl) thiazoles1a

WR SHERMAN, DE DICKSON

文献索引:Sherman,W.R.; Dickson,D.E. Journal of Organic Chemistry, 1962 , vol. 27, p. 1351 - 1355

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被引用次数: 33

摘要

Bromination of the 2-aminonitrofurylthiazole IVc and its acetyl derivative V gave monobromo compounds. These are considered to be the 5-bromothiazoles because of the inactivity of the nitrofuran ring toward bromination and the ease with which aminothiazoles with an unoccupied 5-position undergo halogenati~ n.~ Acetylation of 2-amino-5-bromo-4-(5-nitro-2- furyl) thiazole (VIa) provided an alternate route to the acetyl bromo compound VIb and ...