Propyleneglycolmonolaurate,Isomericmixtures
Propyleneglycolmonolaurate,Isomericmixtures structure
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Common Name | Propyleneglycolmonolaurate,Isomericmixtures | ||
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| CAS Number | 27194-74-7 | Molecular Weight | 258.39700 | |
| Density | 0.931g/cm3 | Boiling Point | 362.5ºC at 760 mmHg | |
| Molecular Formula | C15H30O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 139.3ºC | |
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Investigating the interactions of resveratrol with phospholipid vesicle bilayer and the skin: NMR studies and confocal imaging.
Int. J. Pharm. 484(1-2) , 138-45, (2015) In this work, phospholipid vesicle-based nanoformulations were developed to deliver antioxidant resveratrol (RSV) to the skin. Penetration enhancer-containing vesicles (PEVs) were prepared adding Oramix™ CG110 or Lauroglycol™ FCC to phosphatidylcholine to fav... |
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Preparation, characterization, and in vivo evaluation of a self-nanoemulsifying drug delivery system (SNEDDS) loaded with morin-phospholipid complex.
Int. J. Nanomedicine 6 , 3405-14, (2011) As a poorly water-soluble drug, the oral application of morin is limited by its low oral bioavailability. In this study, a new self-nanoemulsifying drug delivery system (SNEDDS), based on the phospholipid complex technique, was developed to improve the oral b... |
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Self-nanoemulsifying performance of two grades of Lauroglycol (Lauroglycol-90 and Lauroglycol-FCC) in the presence of mixed nonionic surfactants.
Pharm. Dev. Technol. 19(7) , 799-805, (2014) The present study was undertaken to evaluate the impact of various combinations of nonionic surfactants on self-nanoemulsifying performance of two grades of Lauroglycol (Lauroglycol-90 and Lauroglycol-FCC) in glibenclamide (GBN) nanoemulsion. Formulations (L1... |
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Development and Optimization of Solid Self Nanoemulsifying Drug Delivery (S-SNEDDS) Using D-Optimal Design for Improvement of Oral Bioavailability of Amiodarone Hydrochloride.
Curr. Drug Deliv. 12 , 745-60, (2015) The solid-self nanoemulsifying drug delivery system (S-SNEDDS) of Amiodarone hydrochloride (AH) was prepared and evaluated. AH exhibits poor aqueous solubility (0.3-0.5 mg/ml) and therefore variable oral bioavailability. Capmul MCM, Cremophor RH-40 and Propyl... |
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The utility of self-emulsifying oil formulation to improve the poor solubility of the anti HIV drug CSIC.
AIDS Res. Ther. 10 , 14, (2013) CSIC (5-chloro-3-phenylsulfonylindole-2-carboxamide), a non-nucleoside reverse transcriptase inhibitor (NNRTI) has not been advanced as a therapeutic anti-HIV candidate drug due to its low aqueous solubility and poor bioavailability.The objective of this work... |
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Fluorescence spectroscopic investigation of effect of excipients on epidermal barrier and transdermal systems.
J. Investig. Dermatol. Symp. Proc. 3(2) , 128-30, (1998) Excipients are often used in transdermal formulations to overcome the formidable barrier offered by the epidermis in order to achieve the target flux. In this study we describe the use of frequency-domain fluorescence spectroscopy to characterize the effect o... |
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Effect of PGML excipient mixture in a transdermal system on the in vitro transport of estradiol across skin.
Pharm. Res. 12(11) , 1618-22, (1995) To measure the effect of a combination of excipients from a silicone based pressure sensitive adhesive (PSA) on drug transport across skin.Partitioning of propylene glycol monolaurate (PG-ML) from silicone PSA and a solution formulation into the stratum corne... |
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Potential mucoadhesive dosage form of lidocaine hydrochloride: II. In vitro and in vivo evaluation.
Drug Dev. Ind. Pharm. 33(4) , 437-48, (2007) The aim of this study was to develop a controlled release buccal mucoadhesive delivery system for systemic delivery of lidocaine hydrochloride as a model drug. In vitro release and buccal permeation as well as in vivo permeation of LDHCL patches were evaluate... |
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Enhanced transdermal delivery of pranoprofen from the bioadhesive gels.
Arch. Pharm. Res. 29(10) , 928-33, (2006) Percutaneous delivery of NSAIDs has advantages of avoiding hepatic first pass effect and delivering the drug for extended period of time at a sustained, concentrated level at the inflammation site that mainly acts at the joint and the related regions. To deve... |
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Application of mixture experimental design to simvastatin apparent solubility predictions in the microemulsifion formed by self-microemulsifying.
Drug Dev. Ind. Pharm. 33(9) , 927-31, (2007) Self-microemulsifying drug delivery systems (SMEDDS) are useful to improve the bioavailability of poorly water-soluble drugs by increasing their apparent solubility through solubilization. However, very few studies, to date, have systematically examined the l... |