![]() D-methionine structure
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Common Name | D-methionine | ||
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CAS Number | 348-67-4 | Molecular Weight | 149.211 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 306.9±37.0 °C at 760 mmHg | |
Molecular Formula | C5H11NO2S | Melting Point | 273-275ºC | |
MSDS | Chinese USA | Flash Point | 139.4±26.5 °C |
Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational level.
PLoS ONE 4(5) , e5492, (2009) The transcription factor Nrf2 is the master regulator of a cellular defense mechanism against environmental insults. The Nrf2-mediated antioxidant response is accomplished by the transcription of a battery of genes that encode phase II detoxifying enzymes, xe... |
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Antioxidants L-carnitine and D-methionine modulate neuronal activity through GABAergic inhibition.
J. Neural Transm. Gen. Sect. 121(7) , 683-93, (2014) Antioxidants are well known for their neuroprotective properties against reactive oxygen species in cortical neurons and auditory cells. We recently identified L-carnitine and D-methionine to be among agents that provide such protection. Here, we investigated... |
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D-methionine (D-met) significantly rescues noise-induced hearing loss: timing studies.
Hear. Res. 282 , 138-144, (2011) We have previously reported rescue from noise-induced auditory brainstem response (ABR) threshold shifts with d-methionine (d-met) administration 1 h after noise exposure. The present study investigated further d-met rescue intervals at 3, 5 and 7 h post-nois... |
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A novel peptidoglycan binding protein crucial for PBP1A-mediated cell wall biogenesis in Vibrio cholerae.
PLoS Genet. 10(6) , e1004433, (2014) The bacterial cell wall, which is comprised of a mesh of polysaccharide strands crosslinked via peptide bridges (peptidoglycan, PG), is critical for maintenance of cell shape and survival. PG assembly is mediated by a variety of Penicillin Binding Proteins (P... |
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Correction of the consequences of mitochondrial 3243A>G mutation in the MT-TL1 gene causing the MELAS syndrome by tRNA import into mitochondria.
Nucleic Acids Res. 39 , 8173-86, (2011) Mutations in human mitochondrial DNA are often associated with incurable human neuromuscular diseases. Among these mutations, an important number have been identified in tRNA genes, including 29 in the gene MT-TL1 coding for the tRNA(Leu(UUR)). The m.3243A>G ... |
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5'-Untranslated region of the tryptophan hydroxylase-2 gene harbors an asymmetric bidirectional promoter but not internal ribosome entry site in vitro.
Gene 435(1-2) , 53-62, (2009) Tryptophan hydroxylase-2 (TPH2) catalyzes the synthesis of neuronal serotonin, a major neurotransmitter involved in many brain functions and psychiatric disorders. We have previously revealed a critical role of the human TPH2 (hTPH2) 5'-UTR in gene expression... |