Desmetramadol
Desmetramadol structure
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Common Name | Desmetramadol | ||
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| CAS Number | 80456-81-1 | Molecular Weight | 285.81000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H24ClNO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
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Simultaneous Determination of Tramadol and Its Metabolite in Human Urine by the Gas Chromatography-Mass Spectrometry Method.
J. Chromatogr. Sci. 53 , 1037-43, (2015) A sensitive and efficient method was developed for determination of tramadol and its metabolite (O-desmethyltramadol) in human urine by gas chromatography-mass spectrometry. Tramadol, O-desmethyltramadol and medazepam (internal standard) were extracted from h... |
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Pharmacokinetics of tramadol and o-desmethyltramadol in goats after intravenous and oral administration.
J. Vet. Pharmacol. Ther. 31(1) , 45-51, (2008) The aim of this trial was to implement a method to obtain a tool for analyses of tramadol and the main metabolite, o-desmethyltramadol (M1), in goat's plasma, and to evaluate the pharmacokinetics of these substances following intravenous (i.v.) and oral (p.o.... |
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The enantiomers of tramadol and its major metabolite inhibit peristalsis in the guinea pig small intestine via differential mechanisms.
BMC Pharmacol. 7 , 5, (2007) Inhibition of intestinal peristalsis is a major side effect of opioid analgesics. Although tramadol is an opioid-like analgesic, its effect on gut motility is little known. Therefore, the effect of (+)-tramadol, (-)-tramadol and the major metabolite O-desmeth... |
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Method development and validation for simultaneous quantification of 15 drugs of abuse and prescription drugs and 7 of their metabolites in whole blood relevant in the context of driving under the influence of drugs--usefulness of multi-analyte calibration.
Forensic Sci. Int. 244 , 92-101, (2014) In the context of driving under the influence of drugs (DUID), not only common drugs of abuse may have an influence, but also medications with similar mechanisms of action. Simultaneous quantification of a variety of drugs and medications relevant in this con... |