bendroflumethiazide
bendroflumethiazide structure
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Common Name | bendroflumethiazide | ||
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| CAS Number | 73-48-3 | Molecular Weight | 421.415 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 602.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C15H14F3N3O4S2 | Melting Point | 205-207ºC | |
| MSDS | Chinese USA | Flash Point | 318.0±34.3 °C | |
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Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions.
Anal. Chim. Acta 853 , 637-46, (2014) The conditions for the analysis of selected doping substances by UHPSFC-MS/MS were optimized to ensure suitable peak shapes and maximized MS responses. A representative mixture of 31 acidic and basic doping agents was analyzed, in both ESI+ and ESI- modes. Th... |
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Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. II: Analysis of biological samples.
Anal. Chim. Acta 853 , 647-59, (2014) The potential and applicability of UHPSFC-MS/MS for anti-doping screening in urine samples were tested for the first time. For this purpose, a group of 110 doping agents with diverse physicochemical properties was analyzed using two separation techniques, nam... |
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Binding of diuretic antihypertensive bendroflumethiazide to human serum albumin studied by ¹⁹F nuclear magnetic resonance method.
Eur. J. Pharm. Sci. 45(1-2) , 195-200, (2012) Simultaneous specific and nonspecific binding of bendroflumethiazide (BFZ) to human serum albumin (HSA) and concentration profile of BFZ in HSA buffer (pH 7.40) solution were investigated by ¹⁹F nuclear magnetic resonance (NMR) method. The ¹⁹F NMR spectrum of... |
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Mechanism of [m+h]+ formation in atmospheric pressure photoionization mass spectrometry: identification of propionitrile in acetonitrile with high mass accuracy measurement and tandem mass spectrometry and evidence for its involvement in the protonation phenomenon.
J. Am. Soc. Mass Spectrom. 19(11) , 1579-89, (2008) The role of propionitrile in the production of [M+H]+ under atmospheric pressure photoionization (APPI) was investigated. In dopant-assisted APPI using acetone and anisole, protonated acetone and anisole radical cations were the most prominent ions observed. ... |
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Potency of office blood pressure from hydrochlorothiazide and chlorthalidone fails to explain cardiovascular events.
Hypertension 60(3) , e22; author reply e23, (2012)
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Thiazide and thiazide-like diuretics: perspectives on individualization of drug and dose based on therapeutic index.
Hypertension 59(6) , 1089-90, (2012)
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Meta-analysis of dose-response relationships for hydrochlorothiazide, chlorthalidone, and bendroflumethiazide on blood pressure, serum potassium, and urate.
Hypertension 59(6) , 1104-9, (2012) Thiazide and thiazide-like diuretics are widely used in the management of hypertension, but recently the equivalence of hydrochlorothiazide and chlorthalidone for blood pressure (BP) lowering and prevention of cardiovascular disease has been questioned. We pe... |
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Blood pressure control determines improvement in diastolic dysfunction in early hypertension.
Am. J. Hypertens. 22(11) , 1227-31, (2009) Diastolic dysfunction is common in early hypertension. We hypothesized that improvement in diastolic dysfunction is blood pressure (BP) dependent and may occur early with treatment in newly diagnosed untreated hypertensive patients.Forty untreated hypertensiv... |
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Acetazolamide prevents vacuolar myopathy in skeletal muscle of K(+) -depleted rats.
Br. J. Pharmacol. 154(1) , 183-90, (2008) Acetazolamide and dichlorphenamide are carbonic anhydrase (CA) inhibitors effective in the clinical condition of hypokalemic periodic paralysis (hypoPP). Whether these drugs prevent vacuolar myopathy, which is a pathogenic factor in hypoPP, is unknown. The ef... |
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Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria.
Amino Acids 42(5) , 1627-39, (2012) The aim of this study was to assess the effect of the angiotensin II receptor blocker Irbesartan on protein damage by glycation, oxidation and nitration in patients with type 2 diabetes and microalbuminuria. In a double-masked randomised crossover trial of 52... |