(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate
(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate structure
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Common Name | (D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate | ||
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| CAS Number | 143077-65-0 | Molecular Weight | 1557.84000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C77H112N20O15 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Neuromedin B stimulates arachidonic acid release, c-fos gene expression, and the growth of C6 glioma cells.
Peptides 16 , 1133-1140, (1995) The effects of neuromedin B (NMB) on C6 glioma cells were investigated. NMB bound with high affinity (IC50 = 1 nM) to C6 cells whereas BN and GRP were less potent (IC50 = 40 and 100 nM). NMB (1 nM) elevated cytosolic Ca2+ in individual C6 cells and the increa... |
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A new paradigm for stem cell therapy: substance-P as a stem cell-stimulating agent.
Arch. Pharm. Res. 34 , 2003-2006, (2011) Bone marrow is a reservoir for hematopoietic stem cells, endothelial precursor cells, and bone marrow stromal cells (also generally called mesenchymal stem cells), whose positive role in tissue repair is highly anticipated. In this report, we introduce a nove... |
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Substance P mechanisms in the regulation of striated muscle microcirculation.
Microvasc. Res. 41 , 24-28, (1991) The effects of substance P (SP) on microvessels in the cremaster of sodium pentobarbital-anesthetized male, Sprague-Dawley rats were investigated using closed-circuit television microscopy. Topically added SP (bath concentrations of 10(-13) to 10(-8) M) cause... |
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Neural release of substance P causes dilation of arterioles in rat striated muscle.
Regul. Pept. 43 , 65-71, (1993) Substance P, which is present in small nerve terminals and proximal to microvessels in rat strated muscle, may have a vasodilator role if released into the microcirculation. Male, Sprague-Dawley rats were anesthetized with sodium pentobarbital (50 mg/kg, i.p.... |
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Jensen, R.T., et al.
Nature 209 , 61, (1984)
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