Taurolithocholic Acid 3-sulfate disodium
Taurolithocholic Acid 3-sulfate disodium structure
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Common Name | Taurolithocholic Acid 3-sulfate disodium | ||
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| CAS Number | 64936-83-0 | Molecular Weight | 607.73100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H43NNa2O8S2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut.
Proc. Natl. Acad. Sci. U. S. A. 111(20) , 7421-6, (2014) Alterations in the gastrointestinal microbiota have been implicated in obesity in mice and humans, but the key microbial functions influencing host energy metabolism and adiposity remain to be determined. Despite an increased understanding of the genetic cont... |
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Bile salts: natural detergents for the prevention of sexually transmitted diseases.
Antimicrob. Agents Chemother. 43 , 745, (1999) The development of new, safe, topical microbicides for intravaginal use for the prevention of sexually transmitted diseases is imperative. Previous studies have suggested that bile salts may inhibit human immunodeficiency virus infection; however, their activ... |
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Bile acids induce a cationic current, depolarizing pancreatic acinar cells and increasing the intracellular Na+ concentration.
J. Biol. Chem. 280 , 1764, (2005) Biliary disease is a major cause of acute pancreatitis. In this study we investigated the electrophysiological effects of bile acids on pancreatic acinar cells. In perforated patch clamp experiments we found that taurolithocholic acid 3-sulfate depolarized pa... |
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Hepatocyte IKK2 protects Mdr2-/- mice from chronic liver failure.
PLoS ONE 6 , e25942, (2011) Mice lacking the Abc4 protein encoded by the multidrug resistance-2 gene (Mdr2(-/-)) develop chronic periductular inflammation and cholestatic liver disease resulting in the development of hepatocellular carcinoma (HCC). Inhibition of NF-κB by expression of a... |
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Inhibition of taurolithocholate 3-sulfate-induced apoptosis by cyclic AMP in rat hepatocytes involves protein kinase A-dependent and -independent mechanisms Graf, D., et al.
Arch. Biochem. Biophys. 415 , 9, (2003)
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