3-(Trifluoromethyl)phenylboronic acid

3-(Trifluoromethyl)phenylboronic acid Structure
3-(Trifluoromethyl)phenylboronic acid structure
Common Name 3-(Trifluoromethyl)phenylboronic acid
CAS Number 1423-26-3 Molecular Weight 189.93
Density 1.4±0.1 g/cm3 Boiling Point 268.2±50.0 °C at 760 mmHg
Molecular Formula C7H6BF3O2 Melting Point 163-166 °C(lit.)
MSDS Chinese USA Flash Point 116.0±30.1 °C

Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase.

J. Med. Chem. 51 , 7057-7060, (2008)

A series of commercial phenyl-, heteroaryl-, alkyl-, and alkenylboronic acids were evaluated for their FAAH and MGL inhibitory activities. The compounds were generally selective for FAAH, with IC50 in the nanomolar or low-micromolar range. Eight of these comp...